Several epigenetic drugs targeting DNA methylation and histone deacetylation enzymes have been tested in clinical trials.
靶向DNA甲基化和组蛋白去乙酰化酶的几个表观药物已经在临床试验中被测试。
Histone acetylation contributes to expression of gene, while histone deacetylation leads to repression of gene expression.
组蛋白乙酰化促进基因表达，而去乙酰化则抑制基因表达。
Studies had shown that acetylation and deacetylation of histone are of certain value on t, B cell's development, differentiation, maturation, secretion and surface factor's expression etc.
研究表明，组蛋白的乙酰化与去乙酰化状态，可作用于T、B细胞的发育、分化、成熟、分泌及表面因子的表达等多个方面。
The acetylation and deacetylation of histone is charged by a pair of protea se with antistatic function on each other, which are histone transacetylase and histone deacetylase.
组蛋白乙酰化和去乙酰化由一对功能相互拮抗的蛋白酶——组蛋白乙酰基转移酶和组蛋白去乙酰化酶负责。
Histone acetylation and deacetylation can regulate many chromosome functions, such as gene expression and chromosome segregation.
组蛋白乙酰化和去乙酰化可调节染色体的多种功能，例如基因表达和染色体分离等。
Histone acetylation and deacetylation can regulate many chromosome functions, such as gene expression and chromosome segregation.
组蛋白乙酰化和去乙酰化可调节染色体的多种功能，例如基因表达和染色体分离等。
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