Objective to know the background of human gene therapy and the advances in gene therapy study of human hepatocellular carcinoma (HCC).
目的了解人类基因治疗的背景与肝癌基因治疗的研究概况。
With the growing understanding of polymer gene-delivery mechanisms, it is likely that polymer-based gene-delivery systems will become an important tool for human gene therapy.
随着对聚合物基因转移机制的进一步理解,聚合物基因转移体系将成为人类基因治疗的有力工具。
More importantly, though, it adds to the rather small number of human successes with gene therapy.
但更重要的在于这一成果增加了人类基因治疗的微不足道的成功数量。
Investigators evaluated the gene therapy in two mouse models of retinal degenerative disease, as well as cultures of human retinal tissue.
调查评估了在两个视网膜退行性疾病小鼠模型的基因治疗,以及人体视网膜组织的人文研究。
As this trial is the first to treat an eye disease using administration of gene therapy vectors to human retinas, the team have carried out extensive pre-clinical testing.
因为这项试验首次利用基因治疗载体导入人类视网膜进行眼睛治疗,所以该队伍已经进行了大量的临床前试验。
The researchers hope to rapidly translate their findings into a human clinical trial using the same kind of gene therapy modality the investigators have pioneered to treat Parkinson's disease.
研究人员希望可以很快将他们的发现通过调查者所倡导的那样以相同的基因治疗形式转化到人类的临床研究当中去治疗帕金森病。
Gene therapy has shown great potentials in the treatment of a number of human key diseases, such as genetic diseases, cancer and so on, yet there are still some big challenges to face.
基因治疗已在治疗多种人类重大疾病如遗传病、肿瘤等方面显示出良好的应用前景,但也面临着巨大的挑战,主要是如何选择安全、高效、靶向的载体系统。
Conclusion the efficiency and safety of the gene transfer system may provide an optimal experimental system in gene therapy for human leukemia.
结论逆转录病毒介导的基因转移系统是高效、安全的,有助于人类白血病的基因治疗研究。
The article expounds the progress of the study of human genome and post-genome and the current situation of the study of gene therapy and gene drugs.
本文概述了人类基因组及后基因组的研究进展及依此开展基因治疗及基因(组)药物研制等应用开发研究的现状。
As a new gene therapy tool, intrabody brings forth extensive application foreground in the aspects of tumor gene therapy and human HIV gene therapy's experimental study and potential clinical therapy.
胞内抗体作为一种新的基因治疗工具,在肿瘤基因治疗、人艾滋病基因治疗的实验研究及潜在的临床治疗方面展示了广泛的应用前景。
Because of the complexity of tumors and heterogeneity of human, gene therapy is often needed to combined with other therapies to obtain good effect.
由于肿瘤发生的复杂性及患者的异质性,往往要将基因治疗与其它疗法相结合才能收到满意的疗效。
The first human AIDS virus (HIV) infection in patients with the results of clinical trials of gene therapy is finally out.
人类首个艾滋病病毒(HIV)感染患者的基因治疗临床试验结果终于出来了。
Objective To study the effects of gene therapy system mediated by GE7 system and controlled by human growth hormone promoter on somatotroph adenomas of nude mice.
目的利用GE7系统介导的生长激素启动子调控毒性基因治疗裸鼠垂体生长激素腺瘤,评价该系统的治疗效果。
Objective: To construct a replication-competent adenovirus vector carrying human endostatin gene, looking for an effective method for the therapy of colon cancer.
目的:构建携带内皮抑素基因的增殖型腺病毒载体,寻找结肠癌的有效治疗方法。
Objective to study the influence on tumorigenicity of human renal cell carcinoma (RCC) cells transduced with human IL 2 gene, and to intend in forming a basis for RCC gene therapy.
目的研究转人IL2基因对原代肾细胞癌(RCC)细胞致瘤性的影响,为RCC的基因治疗提供依据。
Conclusion: the human fibroblast strain KMB 17 can be used as target cells in BMP 2 gene therapy study.
结论:人成纤维细胞株kmb17可以作为靶细胞用于BMP2基因疗法研究。
Recent progress in gene engineering and related fields such as gene diagnosis, therapy, bioreactor, protein engineering, metabolism engineering, human genome project, bioinformatics is reviewed.
介绍了基因工程及其在基因检测与基因治疗、生物反应器工程、蛋白质工程与代谢工程,基因组计划与生物信息学等相关领域的进展。
To observe the effects of angiostatin gene therapy combined with chemotherapy on intraperitoneal tumor and ascites fluid induced by human ovarian epithelial carcinoma cell line SKOV3 in nude mouse.
研究血管抑素基因联合化疗药物顺铂对人卵巢癌细胞SKOV3诱导的裸鼠腹腔肿瘤和腹水的抑制作用及其相关机理。
Conclusion: MTS1 is able to disturb the cell cycle of HO-8910 and suppress the cell division. This provides a further evidence for gene therapy of MTS1 on human ovarian cancer.
结论:MTS1基因可以改变卵巢癌细胞HO- 8910的细胞周期,这可能为卵巢癌的基因治疗提供了新的实验依据。
Conclusion: MTS1 is able to disturb the cell cycle of HO-8910 and suppress the cell division. This provides a further evidence for gene therapy of MTS1 on human ovarian cancer.
结论:MTS1基因可以改变卵巢癌细胞HO- 8910的细胞周期,这可能为卵巢癌的基因治疗提供了新的实验依据。
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