Objective To study the pathogenesis and the clinical treatment of hyperacute rejection (HAR).
目的探讨肾移植后超急性排斥反应(HAR)的发生机制及其临床对策。
Objective In order to establish the proper animal model of hyperacute rejection(HAR) for xenotransplantation of intestine.
目的用豚鼠对大鼠的异种肠管移植，来探索建立异种肠管移植超急排斥反应模型。
TNF and ICAM-1 play important roles in allograft rejection, however, there are no records Concerning their roles in hyperacute rejection.
TNF和ICAM - 1在同种异体器官移植排斥反应中起重要作用，它们在异种移植排斥反应中的作用，未见文献报道。
In guinea pig to rat heart xenotransplantation model, cobra venom factor is administrated to avoid hyperacute rejection, and thus delayed xenograft rejection model is made.
在豚鼠—大鼠异种心脏移植中，给以眼镜蛇毒因子以避免发生超急性排斥反应，制作延迟性排斥反应模型。
Objective To investigate the effect of purified cobra venom factor (CVF) in rats and the efficacy in preventing hyperacute rejection (HAR) after discordant xenotransplantation.
目的探讨眼睛蛇毒因子（CVF）对血清总补体活性及对豚鼠到大鼠异种心脏移植超急性排斥反应的影响。
Methods The in vitro cultured porcine vascular endothelial cells(PVEC) and human sera were co reacted to set up an in vitro model of hyperacute rejection of pig to human xenotransplantation.
方法用体外培养的猪血管内皮细胞和不同人的血清共同反应，建立猪与人异种移植超急性排斥反应的体外实验模型。
Conclusion the model is easy to prepare and is reliable and helpful for study of the mechanism of hyperacute rejection, for diagnosis, treatment and prevention of hyperacute rejection as well.
结论该方法简单、可靠，有助于研究异种超急性排斥的机理以及关于诊断、治疗和预防超急性排斥的基础研究。
Conclusion the model is easy to prepare and is reliable and helpful for study of the mechanism of hyperacute rejection, for diagnosis, treatment and prevention of hyperacute rejection as well.
结论该方法简单、可靠，有助于研究异种超急性排斥的机理以及关于诊断、治疗和预防超急性排斥的基础研究。
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