In order for a cell to respond directly to insulin it must display an insulin receptor on its surface.
为了使一个细胞能够直接对胰岛素做出反应,因此在它表面必须有一个胰岛素受体。
Insulin receptor substrate 2 (IRS-2) is one of the major substrates of the insulin receptor kinase (1).
胰岛素受体底物2 (IRS - 2)是胰岛素受体激酶的主要底物之一(1)。
The major effects of the PPAR treatments were to increase brain size, preserve insulin and IGF-II receptor bearing neurons, and preserve learning and memory.
PPAR治疗的主要效应是增加大脑的体积,保存胰岛素和IGF - II受体突起神经元,保持学习和记忆。
Exercise can improve insulin resistance, but the specific mechanism of insulin resistance exercise induced on the level of receptor or post-receptor is not sure.
运动能改善胰岛素抵抗,但究其干预的确切机制是发生在胰岛素受体水平还是受体后水平目前尚无定论。
Objective To explore Insulin like growth factor 1 receptor(IGF 1R)gene quantitative expression in human pancreatic cancer cells(PC 3) and the relationship of IGF 1R with apoptosis?tumorigenicity.
目的探讨胰腺癌细胞(PC-3)胰岛素样生长因子-1受体(IGF- 1R)基因的定量表达,及其与细胞凋亡、成瘤性的关系。
AIM: to observe the correlation of the 17 exon gene polymorphism of insulin receptor gene and the Chinese cerebral infarction and primary hypertension.
目的:观察胰岛素受体基因第17外显子基因多态性与中国人脑梗死和原发性高血压的相关性。
Objective: to establish a method of detecting insulin receptor tyrosine kinase (IRTK) activity from erythrocytes.
目的:建立红细胞胰岛素受体酪氨酸蛋白激酶(IRTK)的活性测定法。
AIM: to observe the association of insulin receptor gene exon 17 polymorphism with the transient ischemia attack and essential hypertension in Chinese.
目的:观察胰岛素受体基因第17外显子基因多态性与中国人短暂性脑缺血发作和原发性高血压的关联。
Objective: to investigate the influence of nutrient on the expression of insulin receptor and its related substrate genes in the muscle of mice.
目的:研究不同膳食组成对小鼠肌肉胰岛素受体及其相关底物基因表达的影响。
Objective to study the relationship between soluble tumor necrosis factor receptor (STNFR) 1, 2 and insulin resistance (IR).
目的了解血清可溶性肿瘤坏死因子受体(STNFR)1,2与胰岛素抵抗(IR)的关系。
Objective To observe the changes of insulin and its receptor in hypothalamus of spontaneous hypertensive rats(SHR)and their relationship with blood pressure.
目的探讨下丘脑胰岛素及其受体在高血压大鼠的变化及与血压的关系。
Objective to investigate the change of insulin receptor tyrosine kinase (TK) activity in the pathogenesis of insulin resistance (IR).
目的探讨胰岛素受体酪氨酸激酶(TK)活性变化在胰岛素抵抗(IR)发生中的作用。
Objective to investigate the relationship between the expression of insulin receptor (ir) and the content of tyrosine protein kinase (TPK) in patients with hepatic cirrhosis.
目的探索肝硬化时肝组织细胞胰岛素受体(IR)和酪氨酸蛋白激酶(TPK)含量的变化规律。
Numbers of fasting insulin receptor of high and low affinity in erythrocyte membrane were lower than post-prandial insulin receptor.
红细胞膜高、低亲和力胰岛素受体数目餐前、餐后自身对照均明显下降。
It is speculated that the decrease of insulin receptor may be the major cause of insulin resistance in NIDDM.
据此推测胰岛素受体结合力的降低可能是NIDDM胰岛素抗性的主要原因。
Along with the insulin and its receptor being detected in central nervous system (CNS), the effect of insulin on CNS has caught people's attention.
随着在哺乳动物中枢神经系统发现有胰岛素及其受体存在,胰岛素在中枢神经系统中的作用引起了人们的关注。
Insulin receptor affinity and insulin binding were lower, too.
受体与胰岛素的高亲和力及结合率亦明显降低。
Objective: to probe the role of androgen receptor (ar) and insulin receptor (INSR) in pathogenesis of asymmetric polycystic ovaries (PCO) as local factors.
目的:探讨雄激素受体(AR)和胰岛素受体(INSR)在不对称性多囊卵巢(PCO)局部发病机制中的作用。
Objective to determine the effects of long-term estrogen replacement treatment on blood pressure and expressions of insulin receptor (IR) and insulin receptor substrate-1 (IRS-1) in myocardium.
目的:研究长期雌激素替代治疗对血压及心肌组织胰岛素受体(IR)和胰岛素受体底物1 (IRS 1)表达水平的影响。
To study the clinical features and the role of androgen receptor (ar) and insulin receptor (IR) in auto-para endocrine control of asymmetric polycystic ovaries (PCO).
探讨不对称性多囊卵巢(PCO)的临床特点及雄激素受体(AR)和胰岛素受体(IR)在其发病机制中的作用。
Objective: to study changes of insulin function indicators and explore the relation of insulin receptor substrate-1 (IRS-1) and obese and type 2 diabetes children.
目的:探讨单纯性肥胖及2型糖尿病儿童胰岛素受体底物- 1 (IRS - 1)表达的改变。
Objective To investigate insulin receptor (INSR) genotype exon 17 frequencies in women with polycystic ovary syndrome(PCOS) and to elucidate its role in the pathogenesis of PCOS.
目的探讨胰岛素受体基因外显子17与多囊卵巢综合征(PCOS)发病的关系。
In this paper, the quantity of insulin receptors and the receptor tyrosine kinase activity and its endogenous substrates were comparatively studied in K-562 cells before and after transformation.
对丁酸钠转化前后的人红白血病细胞林k- 562的表面胰岛素受体数量、胰岛素受体酪氨酸蛋白激酶活性及细胞内源性底物进行了研究。
HNMPA-AM3 -the insulin receptor tyrosine kinase inhibitor could block the anti-apoptosis effect of insulin.
胰岛素受体自身酪氨酸磷酸化抑制剂一一HNMPA一AM3可以阻断胰岛素的抗凋亡作用。
"This suggests that insulin receptor signaling in the pituitary is fundamental to the dysregulation of LH secretion associated with the obese state," the researchers wrote.
研究人员称,这表明,脑垂体中胰岛素受体信号对于肥胖状态下的黄体生成素分泌失调至关重要。
In this paper, the tyrosine protein kinase activity of insulin receptor and its endogenous substrates were investigated on the human leukemia cell line K-562 differentiated by sodium butyrate.
本文对丁酸钠诱导分化的人白血病细胞株k- 562细胞的胰岛素受体酪氨酸蛋白激酶性及细胞内源性底物进行了研究。
Objective to find the site of the insulin binding with the insulin receptor via biopanning of disulfide constrained phage display heptapeptides library.
目的用肽库筛选技术寻找与胰岛素受体结合的胰岛素位点。
The level of lymphocyte insulin receptor in peripheral blood were assayed by flow cytomertry.
测定空腹血糖、胰岛素、胰岛素受体;
The level of lymphocyte insulin receptor in peripheral blood were assayed by flow cytomertry.
测定空腹血糖、胰岛素、胰岛素受体;
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