IRS-1 (59g8) Rabbit mAb detects endogenous levels of total IRS-1 protein. The antibody does not cross-react with IRS-2.
兔单克隆抗体识别内源性的IRS - 1总蛋白水平。此抗体与IRS - 2蛋白没有交叉反应。
The tyrosine phosphorylation of IRS-1 was measured by immunoprecipitation and enhanced chemiluminescent immunoblotting technique.
采用免疫沉淀及增强化学发光法检测IRS 1蛋白质酪氨酸磷酸化；
Phosphorylation of IRS-1 at Ser612 by MAPK downregulates insulin signaling and may be part of a response to high glucose/glucosamine levels (11).
1的612位丝氨酸被MAPK磷酸化后会下调胰岛素信号，这可能是对高葡萄糖/葡萄糖胺比值的一种反应。
Objective: to study changes of insulin function indicators and explore the relation of insulin receptor substrate-1 (IRS-1) and obese and type 2 diabetes children.
目的：探讨单纯性肥胖及2型糖尿病儿童胰岛素受体底物- 1 (IRS - 1)表达的改变。
Conclusion Long-term estrogen replacement treatment might protect cardiovascular system through decreasing the blood pressure and inducing the expression of IRS-1 in myocardium.
结论：长期雌激素替代治疗可降低血压、增加心肌细胞IRS 1的表达，从而一定程度上保护心血管。
As well as living longer, the mice without IRS-1 also experienced better health than the normal mice as they aged they had brighter eyes, were more alert and were much healthier overall.
除了寿命更长，缺少IRS - 1的老鼠在老年时也更健康，它们视力更好也更警惕。而缺少IRS - 2的老鼠寿命则有所减少，且表现出肥胖和2型糖尿病。
Objective to determine the effects of long-term estrogen replacement treatment on blood pressure and expressions of insulin receptor (IR) and insulin receptor substrate-1 (IRS-1) in myocardium.
目的：研究长期雌激素替代治疗对血压及心肌组织胰岛素受体(IR)和胰岛素受体底物1 (IRS 1)表达水平的影响。
As illustrated in Figure 1, the same IRS e-File 1120 XML message is stored, exchanged, and used as the basis for display through an XForm.
如图1所示，为了通过XForm进行显示，对同一个IRSe - File 1120XML消息进行存储、交换和使用。
Insulin receptor substrate 2 (IRS-2) is one of the major substrates of the insulin receptor kinase (1).
胰岛素受体底物2 (IRS - 2)是胰岛素受体激酶的主要底物之一(1)。
IRS-2 is essential for normal nutrient homeostasis because it mediates both peripheral insulin action and the effect of IGF-1 on B-cell growth.
IRS - 2对正常营养动态平衡至关重要，因为它能同时介导外周胰岛素的作用和B -细胞中igf - 1的作用。
IRS-2 is essential for normal nutrient homeostasis because it mediates both peripheral insulin action and the effect of IGF-1 on B-cell growth.
IRS - 2对正常营养动态平衡至关重要，因为它能同时介导外周胰岛素的作用和B -细胞中igf - 1的作用。
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