In this work, SOD gelatin microspheres were made with the aim to improve its stability, oral relative bioavailability, and to study the preparation conditions of microspheres.
本工作将SOD制成微球,以提高SOD稳定性和口服相对生物利用度,且在微球制备条件方面作了进一步研究。
Objective:To establish a SPE-HPLC method for the determination of quinapril and its active metabolite quinaprilat in human plasma and to evaluate their pharmacokinetics and relative bioavailability.
目的:建立SPE—HPLC法测定人血浆中喹那普利及其代谢产物喹那普利拉的浓度,以研究喹那普利及喹那普利拉在健康志愿者中的药代动力学和相对生物利用度。
Objective:To establish a SPE-HPLC method for the determination of quinapril and its active metabolite quinaprilat in human plasma and to evaluate their pharmacokinetics and relative bioavailability.
目的:建立SPE—HPLC法测定人血浆中喹那普利及其代谢产物喹那普利拉的浓度,以研究喹那普利及喹那普利拉在健康志愿者中的药代动力学和相对生物利用度。
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