Objective:To establish a selective and sensitive LC-MS/MS method for the determination of cilnidipine in human plasma, and to study the pharmacokinetics in healthy volunteers.
目的：建立西尼地平血药浓度的液相色谱串联质谱（LC-MS/MS）测定法，研究中国健康男性受试者口服西尼地平胶囊后的血浆药动学特点。
METHODS: The concentrations of desloratadine were determined by LC/MS/MS with APCI and the pharmacokinetic parameters were calculated.
方法：采用LC/MS/MS（APCI源）测定地洛他定的血浆浓度，并计算药代动力学参数。
A confirmative method was developed with liquid chromatography tandem mass spectrometry(LC-MS/MS) to detect virginiamycin M1 residue in milk and egg.
建立了牛奶和鸡蛋样品中维吉霉素M1残留的液质联用确证方法。
The concentration of methyclothiazide in blood plasma was measured by an validated LC-MS/MS method and were assessed with non-compartment model to obtain the pharmacokinetic parameters.
方法采用LC-MS/MS法测定血浆中甲氯噻嗪的浓度并用非房室模型计算药动学参数。
Objective: to set up an LC-MS method in order to detect the related substances in clindamycin hydrochloride and to identify those related substances by MS.
目的：建立LC - MS方法检测盐酸克林霉素中有关物质，并利用质谱对有关物质进行初步鉴定。
OBJECTIVE To establish a LC-MS/MS method for the simultaneous determination of guaifenesin, bromhexine, ambroxol in human plasma and to study their pharmacokinetics in healthy volunteers.
目的建立同时测定人血浆中愈创甘油醚、溴己新和氨溴索浓度的LC-MS/MS方法，并应用于人体药动学研究。
Objective To establish a liquid chromatography-tandem mass spectrometry(LC-MS/MS) method for the simultaneous analysis of cocaine(COC) and its metabolite benzoylecgonine(BZE) in urine samples.
目的根据胶体金免疫层析的原理，建立一种可以在现场快速检测可卡因及其代谢物苯甲酰爱康宁的方法。
The stabilities of otilonium bromide in alcohols, water, acetonitrile and plasma were investigated by HPLC, and the degradation products were identified by LC-MS/MS, 1H-NMR and 13C-NMR.
试验中采用HPLC法考察奥替溴铵在醇、水、乙腈及血浆中的稳定性，并用LC-MS/MS、1H-NMR及13C-NMR法对其降解产物进行结构鉴定。
The stabilities of otilonium bromide in alcohols, water, acetonitrile and plasma were investigated by HPLC, and the degradation products were identified by LC-MS/MS, 1H-NMR and 13C-NMR.
试验中采用HPLC法考察奥替溴铵在醇、水、乙腈及血浆中的稳定性，并用LC-MS/MS、1H-NMR及13C-NMR法对其降解产物进行结构鉴定。
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