Liver injury is pathological basis of various hepatic diseases. A characteristic feature of the pathology is hepatocyte degeneration, necrosis, even apoptosis.
肝损伤是各种肝病共同的病理基础,其病理特点为肝细胞变性、坏死,甚至凋亡。
Objective To investigate the influence of nitric oxide on apoptosis of hepatocytes during the rat liver ischemia reperfusion injury.
目的探讨一氧化氮对肝缺血再灌注损伤及肝细胞凋亡的影响。
We herein reported that the apoptosis of mouse liver cell nuclei triggered by cytochrome C in cell free system, which was based on the carrot cell extracts.
用胡萝卜细胞胞浆制备的非细胞体系中,加入纯化的小鼠肝细胞核并以细胞色素C诱导细胞核发生凋亡。
Objective to study effects of selenium and fluoride on oxidative stress and apoptosis in rat liver tissue.
目的研究氟、硒对大鼠肝细胞氧化应激和细胞凋亡的影响。
BACKGROUND&AIM: To study the effect of holmium ions on DNA breakage of mice liver cells and the effect of holmium element on apoptosis of zoic cells in vivo.
背景与目的: 通过研究钬离子溶液对小鼠肝脏细胞DNA的损伤,探讨钬元素对诱导动物细胞凋亡的影响。
Conclusion matrine can inhibit HSC proliferation and induce apoptosis of HSC, which might be one of the mechanisms of matrine to counteract liver fibrosis.
结论苦参碱可抑制HSC增殖、诱导HSC凋亡,可能是苦参碱抗肝纤维化的机制之一。
Objective Massive necrosis and apoptosis of liver cells is the common feature of different kinds of liver diseases, such as viral hepatitis, alcoholic hepatitis, autoimmune hepatitis, etc.
目的:在自身免疫性肝炎和病毒性肝炎引起的肝损伤发病过程中,肝细胞的坏死和凋亡是共同特点。
Conclusion Nitric oxide could increase the release of the hepatic enzymes after liver ischemia reperfusion injury, inhibit the apoptosis of hepatocytes and improve liver ischemia reperfusion injury.
结论一氧化氮可减少肝缺血再灌注损伤后肝酶的释放,抑制肝细胞的凋亡,改善肝缺血再灌注损伤。
SA induced apoptosis in human liver cancer cells, which may be one of the mechanisms of its antitumor effects.
诱导人肝癌细胞凋亡,可能是其抗肿瘤作用机制之一;
Conclusion BHT may cause functional and organic damage of lung and liver, and it can induce apoptosis to pulmonary macrophage in rats.
结论亚急性BHT大剂量染毒可造成大鼠肺、肝等脏器功能性和器质性损伤,BHT可诱发肺巨噬细胞凋亡的产生。
Meanwhile, the pathological changes of liver was observed under light microscope after he staining, and hepatocyte apoptosis was detected by the TUNEL method.
采血后取肝组织,常规石蜡包埋,切片做HE染色观察肝组织的病理变化,采用TUNEL法检测肝细胞的凋亡。
Conclusion the serum mediated with TCM liver-protective drugs could inhibit the TIMP-1 expression of hepatic HSC and promote apoptosis of the activated hepatic HSC.
结论保肝中药复方药物血清能抑制肝星形细胞TIMP 1的表达,并促进活化的肝星形细胞凋亡。
Conclusion: Ammonia may induce the histopathological changes of the brain in rats with liver cirrhosis and the apoptosis of brain cells may be the foundation of these changes.
结论:氨可能诱发肝硬化大鼠脑发生形态变化,脑神经细胞凋亡可能是这种变化的基础。
Liver is regenerated mainly by speeding hepatocyte proliferation rather than reducing hepatocyte apoptosis.
肝再生以肝细胞增殖加速为主,而非肝细胞凋亡减少;
To study the relationship of hepatocyte apoptosis and gene expression of liver cirrhosis and primary hepatic carcinoma.
目的探讨肝细胞凋亡与肝硬变及原癌基因的关系。
After compound 861 treatment for 6 months, the number of activated HSC decreased and the apoptosis of HSC could be seen in the liver biopsy.
复方861治疗6个月后,活化的星状细胞数量显著减少,可观察到其凋亡。
Objective: to observe the state of depression and anxiety in patients with chronic fatigue syndrome typed liver stagnation and spleen deficiency and the lymphocyte apoptosis.
目的:探讨肝郁脾虚型慢性疲劳综合征患者焦虑抑郁状态及淋巴细胞凋亡情况。
Objective: in order to investigate the action of in situ apoptosis in occurrence of liver carcinomas and the biological effect of taxol on BEL-7404 cell line inducing apoptosis.
前言:目的研究肝癌发生过程中原位细胞凋亡活动以及紫杉醇对肝癌细胞系BE L- 7404诱导细胞凋亡的作用。
Thus, the inhibition of apoptosis holds promise as a therapeutic strategy for human liver diseases.
因而,抑制凋亡对人类肝疾病是一个可能的治疗策略。
Objective To study the role of apoptosis of rat liver cell in the pathologic mechanism of fatty liver disease (FLD).
目的研究细胞凋亡在实验性脂肪性肝病大鼠病理机制中的作用。
Objective to investigate the regulatory effects of tuberculin on growth and apoptosis of liver cancer and lung cancer cell lines.
目的探讨结核菌素对肝癌和肺癌肿瘤细胞生长和凋亡的调控作用。
The cell apoptosis index of the transplanted tissues of kidney and liver was significantly smaller in the study group (P< 0.05).
实验组移植肝肾组织中细胞凋亡指数明显低于对照组相应时相(P<0.05);
These results indicated that both the infected and uninfected liver cells could occur apoptosis in patients with viral hepatitis. Further study on the mechanism of liver cell apoptosis is needed.
提示病毒性肝炎患者感染和未感染病毒的肝细胞均可发生凋亡,其机制有待进一步研究。
Object To study the apoptosis induced by sodium artesunate (SA) in human liver cancer cells and its molecular mechanism.
目的研究青蒿酯钠诱导人肝癌细胞凋亡作用及探讨青蒿酯钠诱导人肝癌细胞凋亡的分子机制。
PEG10 gene accelerated the growth of L02 cells and inhibited their apoptosis but it had no conspicuous effect on the non-liver derived cells.
该质粒经过稳定筛选后稳定表达于细胞内,促进人肝细胞的生长,抑制其凋亡,但对非肝脏来源的对照组细胞没有明显影响。
PEG10 gene accelerated the growth of L02 cells and inhibited their apoptosis but it had no conspicuous effect on the non-liver derived cells.
该质粒经过稳定筛选后稳定表达于细胞内,促进人肝细胞的生长,抑制其凋亡,但对非肝脏来源的对照组细胞没有明显影响。
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