Telomerase activity has been detected in almost 90%of all human cancers, but is generally absent in normal somatic cells.

近90%的人类肿瘤可检测到端粒酶活性，而正常体细胞缺乏这种酶的活性。

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Telomere DNA shortening during each round of cell division, due to the end replication problem and as a result, limit the proliferative potential of normal somatic cells.

端粒dna在细胞增殖过程中因为末端复制问题而逐代缩短，因此，限制了正常体细胞的增殖能力。

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Telomerase is a ribonucleoprotein enzyme, which is positively expressed in most malignant tumor cells, while negatively expressed in normal somatic ones.

端粒酶是一种核糖核蛋白复合物，在绝大多数恶性肿瘤细胞中呈阳性表达，而在正常体细胞中则一般为阴性。

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Telomerase is a ribonucleoprotein enzyme, which is positively expressed in most malignant tumor cells, while negatively expressed in normal somatic ones.

端粒酶是一种核糖核蛋白复合物，在绝大多数恶性肿瘤细胞中呈阳性表达，而在正常体细胞中则一般为阴性。

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