The purine and pyrimidine may be complexed with a sugar to produce a nucleoside.
嘌呤和嘧啶可以同一个糖复合,产生一个核苷。
Nevirapine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) of HIV-1.
奈韦拉平是人体免疫缺陷病毒(HIV-1)的非核苷类逆转录酶抑制剂(NNRTI)。
Nucleoside analog monotherapy is the current standard of care for many patients.
核苷类似物单一疗法是目前对很多患者的标准治疗。
The activity of nevirapine does not compete with template or nucleoside triphosphates.
奈韦拉平不与底物或三磷酸核苷产生竞争。
The method was suitable for separating nucleoside analogues from enzyme reaction mixture.
该方法适用于从酶反应混合物中分离核苷类似物。
Nucleoside analogs are important candidates in the searching of antiviral and anticancer drugs.
核苷类似物是一类重要的抗病毒和抗癌药物。
A white, crystalline nucleoside, C9H13N3O5, composed of one molecule each of cytosine and ribose.
胞苷一种白色的晶状核苷,c9h13n3o5,由每个。
The somatic recombination of DNA nucleoside sequences may be one link in the cell differentiation.
DNA碱基序列重组作为决定细胞分化的一个环节是可能的。
To study the efficiency of nucleoside peptide nutrient on antioxidation function of rat by 3 dosage group.
目的采用核肽营养素三个不同剂量组来研究对大鼠抗氧化功能的影响。
AIM To explore if nucleoside diphosphate kinase a (NDPK-A) can potentiate the antitumor action of cisplatin.
目的了解核苷二磷酸激酶a亚基(NDPK A)能否提高顺铂的抗癌效果。
The results suggest that different kinds of nucleoside metabolite may have various effect on metabolic regulation.
提示核苷的不同代谢物在代谢调节中的多样化作用。
This paper summarizes the general separation techniques of nucleoside compounds and the applications at home and abroad.
综述了国内外核苷类化合物分离技术及应用状况。
As competitive inhibitors of natural nucleoside receptors, sugar-modified nucleoside analogues have been well studied in the past few decades.
作为天然核苷受体的竞争性抑制剂,糖环部分化学改造的核苷类似物在过去的几十年中得到了深入的研究。
The invention discloses a pyrimidine nucleoside antibiotic and propiconazole compound bactericide, which belongs to the technical field of pesticide.
一种嘧啶核苷类抗菌素和丙环唑复配杀菌剂,属于农药技术领域。
Purpose:To observe the promoting effect of albumin polypeptide on absorption of nucleoside in intestinal andon cellular immune function in tested mice.
目的:观察白蛋白多肽促进核苷在肠道的吸收及对细胞免疫功能的增强作用。
Objective To study the effects E. coli purine nucleoside phosphorylase suicide gene on human gastric cancer MKN-45 cells as well as the bystander effect.
目的:探讨大肠杆菌嘌呤核苷磷酸化酶自杀基因对胃癌细胞MKN-45的抑制及杀伤作用,并证实旁观者效应。
This paper aims to design and synthesize a non-nucleoside class of coumarin derivatives as the lead compounds with breast cancer and HIV inhibitory activity.
本论文旨在设计合成一类非核苷类对乳腺癌及HIV有抑制活性的具有潜在应用价值的新型香豆素衍生物。
Professor Marcelin: I think this is a good idea because we know the nucleoside and nucleotide analogs are sublimitation and also you got your own limitations.
Marcelin教授:我认为这是个好办法,因为我们知道核苷类药物是次限制的,而每个人会有自己的限制。
Long-term treatment with the second-generation nucleoside analogue lamivudine (lam) efficiently inhibits HBV replication with frequent viral polymerase mutations.
二代拉米夫定的长期应用可以有效地抑制病毒多聚酶突变频繁的HBV发生复制。
The present invention discloses 6-cyproamino-8-chloropurine nucleoside compound, including pharmaceutically acceptable salt, its preparation method and application.
本发明公开了6-环丙胺基-8-氯嘌呤核苷化合物包括药学上可接受的盐及其制备方法与应用。
Effective treatment options for individuals with chronic hepatitis B infection were limited until 1998 when lamivudine, the first nucleoside analogue drug, was introduced.
1998年首个核苷类似物药物拉米夫定推出之前,慢性乙肝病毒感染者可选的有效治疗途径一直都非常有限。
The method was simple, accurate and sensitive with good reproducibility. It can be used for the determination of the residual organic solvents in nucleoside medications.
本方法简单、准确、灵敏高,重现性好,适用于核苷类药物中有机溶剂残留量的测定。
So analogs, including nucleoside and nucleotide analogs are now potent drugs, which suppress complicated viral replication of HVC, I will say in 70% to 90% of the patients.
因此,现在核苷类药物是强效药物,能抑制复杂的丙肝病毒复制,我认为能抑制70%到90%的患者。
Nucleoside analogues are currently the main drug therapy against HBV infection. However, this type of therapy can cause gene mutations in HBV that result in drug resistance.
核苷类药物是目前抗乙型肝炎病毒(HBV)的主要药物,但它可引起HBV基因的变异,从而引起耐药。
Combinations of a protease inhibitor with two nucleoside reverse transcriptase inhibitors are currently recommended for postexposure prophylaxis of relatively high-risk exposures.
对相对高危暴露,目前推荐用一个蛋白酶抑制剂结合两个逆转录酶抑制剂作暴露后预防治疗。
The ultraviolet absorption spectra and molar extinction coefficients, fluorescent spectra as well as quantum yields of nucleoside hydrazones in water, ethanol and dioxane were measured.
测定了在水、乙醇、二氧六环中的紫外吸收光谱与克分子消光系数以及萤光光谱和量子产率。
The chemical modification of sugar moiety in nucleoside or nucleotide is always an important way to discover new lead compounds with anti-viral, anti-tumor and other biological activities.
对核苷类化合物糖环部分的化学改造一直是发现新的具有抗病毒、抗肿瘤或其他生物活性的核苷类先导化合物的重要途径之一。
The chemical modification of sugar moiety in nucleoside or nucleotide is always an important way to discover new lead compounds with anti-viral, anti-tumor and other biological activities.
对核苷类化合物糖环部分的化学改造一直是发现新的具有抗病毒、抗肿瘤或其他生物活性的核苷类先导化合物的重要途径之一。
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