Several studies have described that oxidative DNA damage can induce cancer.
大量研究表明DNA氧化性损伤与肿瘤的发生关系密切。
Thus, oxidative DNA damage adversely affects transcription and DNA replication in melanocytes.
这样氧化损伤的DNA负性影响黑色素细胞的转录和DNA复制。
Objective the genotoxicity and its molecular mechanism of diesel oil vehicle exhaust were discussed through analysing the oxidative DNA damage induced by exhaust components.
目的:通过研究燃汽油机动车尾气成分,及其对DNA分子的氧化损伤,在分子生物学水平上探讨燃汽油机动车尾气污染物的遗传毒性效应与机制。
Objective: the genotoxicity and its molecular mechanism of gasoline vehicle exhaust were studied through examining exhaust components and the oxidative DNA damage induced by them.
目的:通过研究燃汽油机动车尾气成分,及其对DNA分子的氧化损伤,在分子生物学水平上探讨燃汽油机动车尾气污染物的遗传毒性效应与机制。
To study the effects of trichloroethylene on DNA damage in rat hepatocytes and oxidative stress in rat liver tissue.
目的研究三氯乙烯对大鼠肝细胞DNA损伤和肝组织氧化应激的作用。
Oxidant injury, or oxidative stress, occurs when highly reactive molecules called free radicals attack and damage cellular proteins, lipids (fats) and DNA.
氧化损伤,或氧化应激,出现在被称为自由基的高活性分子攻击和破坏细胞蛋白质,脂类(脂肪)和脱氧核糖核酸时。
In this study, we investigated the DNA damage and oxidative stress effects of dust storms fine particles.
本论文对沙尘暴细颗粒物的DNA损伤和氧化应激作用进行了研究。
Similarly, uric acid has been shown to reduce oxidative damage by free radicals in DNA molecules.
同样,据报道尿酸可以降低DNA分子由于自由基造成的氧化损伤。
The DNA oxidative damage is believed that it is repaired mainly by the base excision repair (BER) mechanism with many repairing enzymes.
已知细胞中DNA氧化性损伤主要通过碱基切除修复(BER)来完成,许多修复酶参与了这一修复过程。
Objective To explore the effects of fluoride on oxidative stress and DNA damage in primary hippocampal neurons of rats.
目的研究氟对原代培养大鼠海马神经元氧化应激和DNA损伤的影响。
To evaluate the biocompatibility of dialysis membrane by the oxidative damage of DNA, PS membrane is superior to he membrane.
从DNA氧化损伤的角度来评价透析膜的生物相容性,聚砜膜优于血仿膜。
Active oxygen has an important role in the oxidative damage of biomacromolecules for example DNA, protein and so on.
活性氧在生物大分子如DNA、蛋白质等氧化性损伤中起着非常重要的作用。
Objective To explore the effects of different levels of dietary fat on oxidative damage of DNA in rats.
目的探讨摄入不同脂肪含量食物对大鼠dna氧化性损伤作用的影响。
Oxidative stress can cause DNA damage, such as DNA strand breaks, point mutations, aberrant DNA cross-linking, and mutations in proto-oncogenes and tumor suppressor genes;
氧化应激可以导致DNA链断裂、DNA位点突变、DNA双链畸变和原癌基因与肿瘤抑制基因突变等形式的DNA损伤;
Mycotoxins can affect cells growth, and result in oxidative stress through increase the generation of intracellular reactive oxygen species (ROS), causing DNA damage.
霉菌毒素影响细胞的生长,通过增加细胞内活性氧含量造成氧化应激,对细胞DNA造成损伤。
DNA oxidative damage was detected by single cell gel electrophoresis.
用单细胞凝胶电泳法检测肝细胞中DNA氧化损伤水平。
Objective To detect the DNA strand breaks induced by adriamycin, potassium chromate or hydrogen peroxide and to study the effect ofp tyrosol on DNA oxidative damage in CHL cells.
目的检测阿霉素、重铬酸钾和过氧化氢所致中国仓鼠肺成纤维细胞(CHL)DNA的损伤效应及酪醇对真核细胞DNA氧化损伤的保护作用。
Conclusion fluoride can induce oxidative stress and DNA damage in the hippocampal neurons of rats. The oxidative stress may play an important role in the DNA damage induced by fluoride.
结论氟可引起大鼠海马神经元氧化应激和DNA损伤,氧化应激可能在氟致DNA损伤中起重要作用。
Second, it has a triple strand DNA architecture generated by the synthesis of a short piece of the H strand which is highly sensitive to oxidative damage due to its single strand condition.
线粒体DNA不同步的D环复制形式导致了控制区局部形成三链结构,其单链的构造使其更易受到过氧化物的损害。
This paper mainly reviewed oxidative stress, DNA damage, and their relationship, which could provide a theoretical basis for a further research.
本文主要对氧化应激与DNA损伤之间的联系作一综述,以期为后续的相关研究提供参考。
This paper mainly reviewed oxidative stress, DNA damage, and their relationship, which could provide a theoretical basis for a further research.
本文主要对氧化应激与DNA损伤之间的联系作一综述,以期为后续的相关研究提供参考。
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