Aim To study the bioequivalence of oxymatrine dispersible tablets.
目的考察苦参素分散片生物等效性。
To evaluate the effect of Oxymatrine capsule on chronic hepatitis B (CHB).
目的探讨苦参素胶囊治疗慢性乙型肝炎(CHB)的疗效。
Conclusion Oxymatrine can protect against acute myocardial ischemia injury in rats.
结论氧化苦参碱对大鼠急性心肌缺血损伤具有保护作用。
Objective To investigate the effects of oxymatrine (OMT) on blood pressure in rats.
目的:观察氧化苦参碱(omt)对大鼠血压的影响。
OBJECTIVE: To determine the contents of matrine and oxymatrine in Xuanjing granules by HPLC.
目的:建立以高效液相色谱法测定癣净颗粒中苦参碱、氧化苦参碱含量的方法。
Objective TO optimize the process for preparing liver - targeted oxymatrine nanoparticles (LTON).
目的优选肝靶向氧化苦参碱毫微粒的制备工艺。
OBJECTIVE To prepare oxymatrine sustained-release tablets and evaluate the drag release property.
目的制备氧化苦参碱缓释片剂,并评价其体外释药特性。
Result: Oxymatrine was transformed into matrine by human intestinal bacteria metabolism in vitro.
结果:离体实验结果表明,氧化苦参碱可被人肠内菌代谢成苦参碱。
Results in the selected extraction method, it had a trend that oxymatrine was converted to matrine.
结果在选择的几种提取工艺中,氧化苦参碱有向苦参碱转变的趋势。
Conclusion: Oxymatrine can inhibit cell proliferation and induces apoptosis in Ovarian Cancer cell.
结论:苦参素能抑制卵巢癌细胞增殖,能诱导卵巢癌细胞凋亡。
Aim: To explore the inhibitive effects of oxymatrine (OMT) on allergic contact dermatitis (ACD) in mice.
目的:探讨氧化苦参碱(omt)对小鼠变态反应性接触性皮炎(ACD)的抑制作用。
Objective To determine and compare the anti-HBV effect of famciclovir, foscarnet and oxymatrine in vitro.
目的评价泛昔洛韦、膦甲酸钠及氧化苦参碱的体外抗hbv作用。
RESULTS: The absorption mechanism of oxymatrine complied with the passive diffusion and first order kinetics.
结果氧化苦参碱在肠道的吸收呈现一级吸收动力学特征且吸收机制为被动转运。
Objective To observe the effects of matrine and oxymatrine on the proliferation and the apoptosis of A549 cells.
目的观察比较苦参碱及氧化苦参碱对A5 49细胞系增殖能力的影响及其对A5 49细胞凋亡的诱导效应。
Objective: To observe the efficacy and safety of oxymatrine combined with thymosin in treatment of chronic hepatitis.
目的:探讨苦参素联合胸腺肽治疗慢性乙型肝炎的疗效。
ResultsThe matrine and oxymatrine of cultivated and field Shandougen have not difference in cultivation and field by UV.
结果引种栽培的山豆根与野生山豆根不同部位的苦参碱及氧化苦参碱二者含量无明显差异。
Objective To evaluate the efficacy of oxymatrine on treating chronic hepatitis B with hepatic fibrosis and its mechanism.
目的探讨氧化苦参碱治疗慢性乙型肝炎肝纤维化的效果及其机制。
METHODS: The absorption kinetics and absorption site of oxymatrine were investigated using in situ perfusion method in rats.
方法采用大鼠在体肠灌流吸收实验,研究了氧化苦参碱的吸收部位和吸收动力学特征。
Objective To observe the clinical effect of both oxymatrine and lamivudine on hepatic fibrosis induced by chronic hepatitis b.
目的观察拉米夫定联合氧化苦参碱对抗慢性乙型肝炎(乙肝)肝纤维化的临床疗效。
A primary duck hepatocyte-DHBV (PDH-DHBV) infection model was established to investigate the antiviral effects of Oxymatrine (OM).
通过建立鸭原代肝细胞-DHBV感染模型研究氧化苦参碱抗dhbv的作用。
Methods Radix Sophorae Flavescentis and Cortex Pseudolaricis were identified by TLC. The content of oxymatrine was determined by HPLC.
采用薄层色谱法对方中的土荆皮、苦参进行定性鉴别;采用高效液相法测定癣湿特效药水中氧化苦参碱的含量。
Results:MTT assay showed that inhibited human ovarian careinoma HO8910 cells growth by oxymatrine alone and combinated with radiation.
结果:在苦参素、放射治疗及二者联合作用下均能抑制HO8910细胞生长,二者联合作用下抑制HO8910细胞生长作用更明显。
OBJECTIVE:To study clinical effect of glycyron(SNMC) combined with oxymatrine complex(Bo'er tai li) on chronic HB and adverse reactions.
目的:探讨复方甘草酸苷注射液(美能)联合苦参素(博尔泰力)治疗慢性乙型肝炎的临床疗效与不良反应。
The Influence of herba saururi was much higher than that of fructus cnidii and polygonum chinense on the content of matrine and oxymatrine.
处方中三白草对苦参中苦参碱及氧化苦参碱含量的影响大于蛇床子、火炭母。
The effect of Oxymatrine(OMT), isolated from Sophora flavescens Ait, on the hepatic microsomal drug-metabolism enzyme have been investigated.
氧化苦参碱是自中药苦参中提取的一种生物碱,本文就其对小鼠肝微粒体药物代谢酶的影响进行了探讨。
OBJECTIVE To investigate the formulation and preparation technique of anionic oxymatrine liposomes, and determine its physicochemical properties.
目的考察氧化苦参碱负电荷脂质体的处方和制备工艺,并研究其理化性质。
Objective To study the effect of microfiltration-macroporous resin method in purification of oxymatrine and general flavone in sophora flavescens.
目的考察微滤-大孔树脂法精制苦参中氧化苦参碱、苦参总黄酮的效果。
Objective To study the effect of microfiltration-macroporous resin method in purification of oxymatrine and general flavone in sophora flavescens.
目的考察微滤-大孔树脂法精制苦参中氧化苦参碱、苦参总黄酮的效果。
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