No effects of risperidone on lithium or valproate exposure were observed, despite a 20% increase in valproate peak plasma concentration.
我们没有观察到利培酮合用锂盐或丙戊酸钠的不良反应,尽管在丙戊酸钠上血浆浓度峰值增加20%。
Bioavailability determinations based on the peak plasma concentration can be misleading, because drug elimination begins as soon as the drug enters the bloodstream.
单靠峰时血浆浓度来确定生物利用度会导致误解,因为药物一进入血流就会开始药物消除。
Only recently have the peroral or dermal use been evaluated. Drugs encapsulated into SLN showed a reduced peak plasma concentration and prolonged therapeutic drug level following oral administration.
近年来,SLN的口服和经皮给药逐渐受到重视,研究发现,口服经过SLN包裹后的药物能降低其血药浓度峰值,并延长药物作用时间。
Only recently have the peroral or dermal use been evaluated. Drugs encapsulated into SLN showed a reduced peak plasma concentration and prolonged therapeutic drug level following oral administration.
近年来,SLN的口服和经皮给药逐渐受到重视,研究发现,口服经过SLN包裹后的药物能降低其血药浓度峰值,并延长药物作用时间。
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