Recently, poly (d, l-lactide) -poly (ethylene glycol) (PLA-PEG) block copolymers have been widely applied owing to the favorable biodegradability and biocompatibility.
聚乳酸-聚乙二醇嵌段共聚物因具备良好的生物可降解性和相容性而得到广泛应用。
Syntheses and properties of PLA-PEG block copolymers were introduced, and their applications for micelles, microspheres and nanoparticles in drug delivery system were also reviewed.
介绍PLA - PEG嵌段共聚物的合成和性质,综述其作为胶束、微球、纳米粒等的载体在药物释放系统中的应用。
The results indicated that the addition of PEG has little effect on the molecular structure of PLA filament whose mechanical property has been improved, especially the elongation at break.
结果表明:PEG的加入对PLA纤维分子结构的影响不明显,但却明显改善了PLA纤维的力学性能,特别是断裂伸长率有明显的提高。
This article reviewed pharmaceutical research and application of biodegradable PEG-PLA block copolymers and its micro - or nano-particles as drug delivery system.
综述可生物降解嵌段共聚物聚乙二醇-聚乳酸(PEG - pla)及其微粒给药系统在药剂学中的研究与应用。
The microspheres of PEG-PLA block copolymers can enhance the stability of protein and polypeptide, and profit the release of poorly water-soluble pharmaceuticals.
该嵌段共聚物微球能提高蛋白、多肽的稳定性,有利于难溶性药物释放。
The microspheres of PEG-PLA block copolymers can enhance the stability of protein and polypeptide, and profit the release of poorly water-soluble pharmaceuticals.
该嵌段共聚物微球能提高蛋白、多肽的稳定性,有利于难溶性药物释放。
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