Objective To screen the formulation for tanshinone self-emulsifying drug delivery system (SEDDS) and evaluate its stability.
目的筛选丹参酮自乳化药物传递系统的处方,考察其稳定性。
RESULTS The optimum self-emulsifying drug delivery system was composed of olive oil(60%), Tween 85(35%), absolute alcohol(5%).
结果优选出虾青素自乳化释药系统处方为橄榄油(60%)、聚山梨酯85(35%)、无水乙醇(5%)。
Objective: To design the formulation of self emulsifying drug delivery system for silymarin and evaluate its dissolution.
目的:设计水飞蓟素自乳化系统处方并评价其溶出度。
Result: The silymarin self emulsifying drug delivery system was composed of Tween 85, olive oil and glycerin but not including silymarin.
结果:水飞蓟素自乳化系统除主药外,主要由吐温85、橄榄油、甘油组成。
The characters, mechanism and formulation design of self emulsifying drug delivery system were reviewed. Its quality and affecting factors, and pharmaceutical applications were discussed.
对自我乳化药物传递系统的特点,形成机制,目前采用的处方组成等进行了综述,并对该系统的质量,影响因素及制剂学应用作了一般性介绍。
The characters, mechanism and formulation design of self emulsifying drug delivery system were reviewed. Its quality and affecting factors, and pharmaceutical applications were discussed.
对自我乳化药物传递系统的特点,形成机制,目前采用的处方组成等进行了综述,并对该系统的质量,影响因素及制剂学应用作了一般性介绍。
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