目的提高三七总皂苷的收率及纯度。
ObjectiveTo increase the yield and the purity of total saponin of Panax notoginseng.
前言：目的：制备三七总皂苷分散片。
Objective: to prepare for the total sapogenin disperse tablet of Notoginseng.
目的：研究三七总皂苷(PNS)对神经细胞的保护作用。
OBJECTIVE: to study the neuroprotective effects of saponins of Panax notoginseng (PNS).
分别建立了三七总皂苷缓释片、重楼皂苷分散片的质量标准。
The quality standard of Panax notoginseng sustained-release tablets and Paris Polyphylla saponin dispersible tablets were different established.
目的研究三七总皂苷对大鼠肝脏低温保存的影响及其作用机理。
Objective to investigate the effects and mechanism of Panax Notoginseng saponins on rat liver during cold preservation.
前言：目的：确立血塞通滴丸(三七总皂苷)的最佳成型工艺。
Objective: to establish the optimum preparation process for Xuesaitong Dropping Pills (total saponin of Radix Notoginseng).
方法对主要成份大黄素、大黄酸、三七总皂苷等进行定性鉴别；
METHOD The main components, emodin and rhein and total notogisennoside were qualitatively identified.
目的：了解三七总皂苷在抗肝损伤方面的药理作用及临床进展情况。
Objective:To know about the pharmacological action and clinical advances in Parax notoginseng for anti-hepatic lesion.
目的探讨三七总皂苷、黄芪防治2型糖尿病动脉粥样硬化的作用机制。
Objective to investigate the role and mechanism of Astragalus (AS) and Panax Notoginseng Saponins (PNS) in treatment of type 2 diabetic atherosclerosis.
目的：本实验制备了三七总皂苷分散片，以达到提高药物溶出，改善吸收。
OBJECTIVE: to prepare Radix Notoginseng total Saponin Dispersible tablets to enhance the dissolution rate and improve its absorbability.
目的研究三七总皂苷(PNGS)对大鼠肝脏低温保存的影响及其作用机理。
Objective to investigate the effects and mechanism of Panax Notoginseng saponins (PNGS) on rat liver during cold preservation.
三七总皂苷注射剂已广泛用于临床，而其非注射剂型的开发应用仍非常有限。
Panax notoginseng saponin (PNS) injection has been widely used in clinic, but the development and application of non-injectable PNS formulations are still insufficient.
目的研制三七总皂苷生物黏附片，考察其体外释药动力学、对离体肠黏膜的黏附力。
OBJECTIVE To prepare the Panax Notoginseng Saponines (PNS) bioadhesive tablets, and to study their release kinetics and bioadhesive tablets force to rabbit small intestine in vitro.
结论药代动力学和药效学结果证明，三七总皂苷鼻腔给药制剂具有很好的开发前景。
Conclusion The results of pharmacokinetics and pharmacodynamics demonstrated that PNS intranasal preparation has a pretty prospect to develop.
目的：研究三七总皂苷（PNS）对人脐静脉内皮细胞（HUVEC）的增殖作用。
Objective: To investigate the proliferation efficiency of total saponins of Panax notoginseng (PNS) on human umbilical vein endothelial cell (HUVEC).
目的：研究三七总皂苷(PNs)脂质体的生理适应性及其对心脑血管的保护作用。
AIM: to investigate the physiological compatibility and protective effects on cardio-cerebrovascular diseases of Panax notoginseng (PNS) liposomes in animals.
目的：研究三七总皂苷(PNS)脂质体的制备方法并对其生理适应性进行初步考察。
AIM: to study the preparation and physiological compatibility of pulmonary administration with Saponius of Panax Notoginseng (PNS) liposomes.
方法：采用高效液相色谱法测定我们制备的三七总皂苷分散片和血栓通制剂的溶出度。
METHODS: The dissolution rates of Radix Notoginseng total Saponin Dispersible tablets and Xueshuantong preparation were determined by HPLC.
三七总皂苷(PNS)是三七的主要生理活性成分，广泛地应用于心血管疾病的治疗。
Panax notoginseng saponins (PNS) are the chief active constituents of Panax notoginseng, and have been widely used for the treatment of cardiovascular diseases.
目的：研究复方配伍对三七总皂苷（PNS）的胃肠道稳定性、膜渗透性及脂溶性的影响。
Objective:To investigate the effects of compound compatibility on the stability in gastrointestinal tract, membrane permeability and lipophilicity of panaxnotoginseng saponins (PNS).
目的探讨三七总皂苷(PNS)对急性脑梗死患者单核细胞CD 14及TLR4的影响。
Objective It is to discuss the influence of total saponins panax notoginseng (PNS) on CD14 and TLR4 of mononuclear cell in acute cerebral infarct patients.
方法以三七总皂苷含量为评价指标，采用正交试验法优选超声波提取三七总皂苷的工艺条件。
Methods the optimal process of extracting total saponins was studied by orthogonal test, as the content of the total saponins being the measurement.
主要观察指标：三七总皂苷对阿尔茨海默病大脑胆碱能神经元分布和胆碱乙酰基转移酶的影响。
MAIN OUTCOME MEASURES: Effect of PNS on distribution of cholinergic neuron and ChAT content in cerebral tissue of AD rat models.
目的：观察三七总皂苷(PNS)对老年性痴呆(AD)大鼠模型大脑胆碱能神经病理损害的保护作用。
Objective: to observe the protective effect of Panax notoginseng saponins (PNS) against pathological lesion of cholinergic neuron in rat model with Alzheimer's disease (AD).
结果：三七总皂苷可有效降低脑缺血再灌注损伤大鼠的脑梗死体积，明显减轻脑缺血区血脑屏障破坏的程度。
Result: PNS could reduce infarct volume of cerebral ischemia-reperfusion injury in rats, reduce the extent of the damage in blood-brain barrier significantly.
三七以乙醇渗漉提取后，用d _(101)大孔吸附树脂进行纯化，所得三七总皂苷含量达90%以上，杂质较少。
PNS was extracted with ethanol from Radix notoginseng by infiltrating, and purified with D101 macroporous resin, its content up to 90%.
方法：应用MTT比色法研究三七总皂苷、丹参注射液、苦参碱对体外培养大鼠肝癌细胞CBRH7919影响的量效关系。
Methods: Different concentrations of PNS, matrine and Danshen injection were used to detect the antineoplastic effects on CBRH7919 cells in vitro by using MTT Method.
方法：检索1994 ~ 2006年国内公开发表的医学期刊报道应用三七总皂苷类注射剂致不良反应案例，对其进行统计分析。
METHODS: ADR cases induced by SPN injection that retrieved from domestic medical journals between 1994 and 2006 were analyzed statistically.
方法：检索1994 ~ 2006年国内公开发表的医学期刊报道应用三七总皂苷类注射剂致不良反应案例，对其进行统计分析。
METHODS: ADR cases induced by SPN injection that retrieved from domestic medical journals between 1994 and 2006 were analyzed statistically.
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