大学即将破产然后关门大吉。
数千计的工厂就此关门大吉。
同样也有成千上万的公司破产或关门大吉。
今年三月，豪瑞所合并谈判失败，关门大吉。
After failed merger talks, Howrey shut its doors this March.
数以千计大大小小的唱片店也都关门大吉了。
预计到2016年，338间门店将关门大吉。
338 establishments are projected to close between 2010 and 2016.
因为顾客投诉服务太差，这家小吃点不得不关门大吉。
(service) Because the customers complained about its poor service, the snack bar had to close down.
由于经济不景气，许多高档的家具店去年都关门大吉了。
Many upscale furniture stores closed last year due to the economic recession.
动荡的市场导致一些基金经历了令人尴尬的损失甚至索性关门大吉。
Choppy markets have caused some funds to experience embarrassing losses or even shut up shop entirely.
有人想接管我的生意，但是我们没有联系到他们，所以我只能直接关门大吉。
Someone had offered to buy my business earlier, but I could not contact them, so I simply closed it down.
切记：资本短缺是企业在第一年就举步维艰甚至关门大吉的主要原因之一。
Keep in mind: a lack of capital is one of the top reasons why businesses struggle or close during the first year.
2009年，Subhiksha受到管理不当和涉嫌欺诈的指控而关门大吉。
It was closed in 2009 amid accusations of mismanagement and fraud.
大公司的站点能够支付起这项新费用，而与此同时，小公司的站点只能关门大吉。
Majorcorporate sites would be able to pay the new fees, while little-guysites could be shut out.
很多人猜测这两位创始人会通过诉讼让Skype关门大吉，投资者将一无所有。
Many speculated that the founders would use their claim to shut down Skype and leave investors with nothing.
为了熬过最艰难的时刻，其中许多厂子都削减了生产量，有的甚至直接关门大吉。
Many have slashed production, to survive the bitter winter of the industry; some have closed their doors for good.
上海一家餐厅在获得米其林星级之后第二天就关门大吉，原因是缺少必须的营业执照。
Shanghai restaurant has closed down a day after being awarded a Michelin star, reportedly because it lacked the necessary licences to operate.
这些天来，我们到处都能看到有一些报纸关门大吉，停止出版，或是变成纯在线的报纸。
These days, everywhere you look it seems that some newspaper is closing its doors, stopping its presses, or maybe just going online-only.
谁也没有办法来解决这个争论满足每一个人的要求，所以，这家理发沙龙就关门大吉啦。
The arguments couldn't be settled to everyone's satisfaction, so the salon was forced to close.
始创于1865年的《旧金山纪事报》为避免关门大吉的局面，正进行着新一轮的裁员。
The San Francisco Chronicle, founded in 1865, is trimming its already pared-down staff in an attempt to avoid closure.
我知道如果我接受了他们的要求，在今天开业，那么他们明天会卷土重来，让我关门大吉。
I knew that if I accepted their request to open my facilities today, they'd have the power to return tomorrow, to tell me to close them.
按照Flexner报告的精神，当时，许多医学院要么进行了合并要么直接关门大吉了。
Following the Flexner report, many medical schools merged or were closed outright.
处于竞争面的主流媒体很高兴看到维基关门大吉，然后就是来自其自我毁灭性的失误的兴奋。
Rival mainstream media have been happy to feed off the leaks but then delight in his self-destructive mistakes.
你需要根据情况不断改进公司的服务。否则，你就会发现客户不断减少(最终，关门大吉)。
Make the necessary changes to improve service or else you may find yourself with fewer customers (and eventually, out of business).
当然我们可以把那笔债务一笔勾销，然后让美联储关门大吉，不过华盛顿极少有人对此感兴趣。
Of course we could repudiate that debt and shut down the Federal Reserve, but very few in Washington D.C. have any interest in doing that.
洗衣机的普及让自主洗衣店关门大吉，经济危机前的自置居所率在世界各地都呈现出增长趋势。
Laundromats have been closing down as people buy their own washing machines. Home ownership was, until the financial crisis, rising nearly everywhere.
路过衣服专卖店，看着那些店员闲着打瞌睡，我总担心生意清淡，总有一天，她们会关门大吉。
Passing clothing store, looking at those staff idle doze off, I always worried that business is tepid , one day, they would close down.
路过衣服专卖店，看着那些店员闲着打瞌睡，我总担心生意清淡，总有一天，她们会关门大吉。
Passing clothing store, looking at those staff idle doze off, I always worried that business is tepid , one day, they would close down.
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