目的:制备米托蒽醌固体脂质纳米粒并优化其处方组成。
OBJECTIVE to prepare and optimize the composition of mitoxantrone solid lipid nanoparticles.
方法用水性溶剂扩散法,制备得到甘油单硬脂酸酯固体脂质纳米粒。
Methods Monostearin solid lipid nanoparticles was prepared by solvent diffusion method in aqueous system.
方法以硬脂酸为载体采用溶剂乳化法制备水飞蓟素固体脂质纳米粒,并用葡聚糖凝胶层析法测定其包封率。
Method Silymarin SLN was prepared through the solvent-emulsifying method with stearic acid as the carrier, and the encapsulation rate was determined with the Sephdex gel chromatogram.
结论溶剂乳化法适用于水飞蓟素固体脂质纳米粒的制备。
ConclusionThe solvent - emulsifying method is suitable for preparation of silymarin SLN.
固体脂质纳米粒通常是由固体脂质材料经高压乳匀法制备而成。
Solid lipid nanoparticles (SLN) are nanoparticles generally made from solid lipids by high pressure homogenization.
目的制备咪喹莫特固体脂质纳米粒,并考察其理化性质及其对透皮的影响。
OBJECTIVE To prepare imiquimod-loaded solid lipid nanoparticles and investigate their properties and transdermal permeation.
目的:制备10 -羟基喜树碱的半固体脂质纳米粒(HCPT -SSLN)并考察其稳定性。
Objective: to prepare 10-hydroxycamptothecin-semisolid lipid nanoparticles (HCPT-SSLN) and investigate its stability.
本发明公开了一种黄芩天然活性成分的固体脂质纳米粒及其制剂制备方法。
The present invention discloses nanometer solid lipid particle of active skullcap components and its preparation.
摘要:目的制备地西泮固体脂质纳米粒,评价其制剂学性质,并探讨其经鼻腔给药后的药动学过程。
ABSTRACT: OBJECTIVE To prepare diazepam solid lipid nanoparticles, evaluate the pharmacy characters and study the pharmacokinetics after intranasal administration.
摘要:目的制备地西泮固体脂质纳米粒,评价其制剂学性质,并探讨其经鼻腔给药后的药动学过程。
ABSTRACT: OBJECTIVE To prepare diazepam solid lipid nanoparticles, evaluate the pharmacy characters and study the pharmacokinetics after intranasal administration.
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