这些发现表明肿瘤干细胞基因标签可用于鉴别具有高复发和转移风险的患者。
These findings suggest that this cancer stem cell gene signature may be used to identify patients at the highest risk for disease recurrence and metastasis.
肿瘤转移抑制基因能抑制肿瘤细胞的转移，由于肿瘤转移抑制基因的突变或缺失，从而导致肿瘤的浸润和转移。
Tumor metastasis suppressor gene can inhibit the metastasis of tumor cells, mutations or deletions of this kind of genes can lead to tumor invasion and metastasis.
该基因的表达与肿瘤组织学分型、浸润方式、肿瘤大小及淋巴结转移个数等无关（P>0.05）。
In contrast, the reduced expression of the LO gene had no relation to histological classification, invasion pattern, tumor size, and number of metastasis lymph nodes(P >0.05).
SIPA1在HCC中发挥肿瘤抑制基因的作用，且对抑制HCC的复发转移有重要作用。
SIPA1 probably inhibits the metastasis and recurrence of HCC as a tumor suppressor gene.
肿瘤的侵袭和转移是多基因多因子共同作用的结果。
The invasion and metastasis of neoplasm in the interactive effect by diverse gene and factors.
我们以特定基因族里的转位基因为代表用主成分分析法计算其与肿瘤转移时间的表达。
We calculated metagenes as a surrogate for all genes contained within a particular cluster and visualized the relative expression in relation to time to metastasis with principal component analysis.
结论：外源性CAR基因的导入可以增强卵巢癌细胞SKOV3间的粘附性，从而抑制肿瘤细胞的侵袭转移表型。
CONCLUSION: Transfected CAR gene may enhance the adhesion ability of ovarian cancer SKOV3 cells, therefore, inhibit the malignant metastatic phenotype of SKOV3 cells.
这种靶向性的策略包括目的基因对肿瘤细胞的靶向转移，目的基因在肿瘤细胞中的特异表达，以及基因修饰细胞分泌的肿瘤靶向治疗分子。
This can be achieved by tumor targeted gene transfer or tumor specific gene expression, as well as secretion of tumor targeted therapeutic molecules by autologous normal cells.
这些基因分别与细胞增殖、基因转录、凋亡、信号转导、DNA损伤修复、肿瘤分化和浸润转移及细胞周期调节等相关。
These genes were involved in cell proliferation, gene transcription, apoptosis, signal transduction, DNA damage and repair, tumor differentiation and metastasis, cell cycle, and so on.
虽然有事实证明一些微小rna能够起癌基因或者抑癌基因，但是其在肿瘤的侵袭和转移中的作用尚未有研究。
Although there is emerging evidence that some microRNAs can function as oncogenes or tumour suppressors, the role of microRNAs in mediating cancer metastasis remains unexplored.
目的：研究舌鳞状细胞癌(TSCC)有丝分裂活化蛋白激酶(ERK)基因的表达及其与肿瘤病理分型、临床分期、颈淋巴结转移的关系。
PURPOSE: the aim of this study is to investigate the relationship between ERK1, ERK2 gene expression and tumor behavior such as invasion, metastasis in tongue squamous cell carcinoma (TSCC).
目的探讨肿瘤转移相关基因编码蛋白在卵巢癌和宫颈癌转移中的表达规律及其临床意义。
Objective To study the expression regularity and its significance of tumor metastasis related genes in tumor tissues of patients with ovarian or cervical cancer.
本文对骨桥蛋白在肿瘤中的信号转导、基因表达与调控以及肿瘤转移过程中的作用予以综述。
This article reviews its role in the signal transduction, expression and regulation in tumors and the roles in tumor metastasis.
目的：在肿瘤转移过程的研究中，许多证据已经证实了肿瘤转移抑制基因的重要性。
Purpose: Ample evidence supports an important role of tumor metastasis suppressor genes in cancer metastatic processes.
结论对BRMS1基因的深入研究有助于进一步深化对乳腺癌转移的认识，为肿瘤转移的分子诊断和基因治疗提供新的思路。
Conclusion Further studies on BRMS1 may be helpful to understand the metastasis of breast cancer, which may provide a new way for the diagnosis and treatment of breast cancer.
而另外30%的结肠转移性肝肿瘤病人则出现了一些新的基因突变。
In the tumors from the other three patients, a few new genetic mutations appeared in the liver metastases.
目的探讨反义vegf基因和内皮抑素基因联合转染在抑制肿瘤血管生成和肿瘤生长转移中的作用。
Objective to explore the co operative inhibitory effect of antisense VEGF gene and endostatin gene transfection on tumor angiogenesis, tumor growth and metastasis of lung cancer.
垂体肿瘤转化基因1 (PTTG1)具有促进肿瘤生长和转移的作用。
Pituitary tumor transforming gene 1 (PTTG1) is a proto-oncogene and plays roles in promoting tumorigenesis and metastasis.
目的探讨肿瘤多肽致敏的白介素12 （IL 12 ）基因修饰的树突状细胞（DC）对自发性肺转移癌的治疗作用。
Objective To investigate the treatment of spontaneous metastatic lung cancer by tumor antigen-pulsed, interleukin-12(IL-12) gene-modified dendritic cells (DC).
TGF配体虽然在早期肿瘤中作为肿瘤抑制基因发挥作用，但其在进展期肿瘤中却变成有效的促转移因子。
TGF ligands act as tumor suppressors in early stage tumors but are paradoxically diverted into potent prometastatic factors in advanced cancers.
近来对新发现的肿瘤转移抑制基因NM 23和抑癌基因pten引起了人们极大关注。
Recently, the new discovered NM23 gene (a tumor metastasis suppressor gene) and PTEN gene (a tumor suppressor gene) cause people's attention extensively.
癌转移抑制基因是一类只抑制癌细胞的转移而不影响肿瘤的发生与生长的基因。
Tumor metastasis suppressor gene is a kind of genes that only suppresses metastasis without affecting tumorigenicity and tumor growth.
MTA1基因是最近发现的一个肿瘤转移相关基因，与许多肿瘤的浸润和淋巴结转移程度有关。
The MTA1 gene has been recently identified as metastasis-associated gene, which is related to the degree of invasion and lymphatic metastasis in various carcinomas.
目的研究乳腺癌耐药蛋白(BCRP)基因在乳腺癌组织中的表达水平，探讨其与肿瘤病理分期、淋巴结转移的关系。
Objective to study the expression levels of breast cancer resistance protein (BCRP) in breast cancer, and to investigate the relation between BCRP and clinical stages and lymph node metastasis.
治疗21d后处死裸鼠，观察肝脏转移率和转移结节数，RTPCR检测CD基因在肿瘤组织的表达，光镜及电镜下观察肿瘤病理学的变化。
After treated for 21 d, the mice were sacrificed and liver metastasis rate and liver metastasis nodule Numbers were observed. Expression of CD gene in liver metastasis tissues was determined by RTPCR.
通过慢病毒整合位点鉴别，我们得以分辨转移和非转移瘤并明确可区分这两种不同类型肿瘤的基因表达改变。
Identification of the lentiviral integration sites allowed us to distinguish metastatic from non-metastatic tumours and determine the gene expression alterations that distinguish these tumour types.
转移抑制基因是一类只抑制癌细胞的转移但不影响肿瘤发生和生长的基因。
Tumor metastasis suppressor genes is a kind of genes that only suppresses tumor metastasis without affecting tumorigenesis and tumor growth.
摘要乳腺癌的转移是一个较为复杂、由多基因参与及多步骤完成的过程，转移相关基因对转移的调控是肿瘤发生转移的分子基础。
Breast cancer metastasis is a complicated process driven by multiple genes and follows multiple steps. The regulation of metastasis-associated genes is the molecular basis for metastasis.
我们报道的唯一一例转移性基底细胞癌肉瘤病例，并对原发肿瘤的两种成分及转移成分进行了第二代基因测序。
Herein, we report a unique case of metastatic basal cell carcinosarcoma, in which we analyzed the 2 components of the primary tumor as well as the metastasis by next-generation sequencing.
我们报道的唯一一例转移性基底细胞癌肉瘤病例，并对原发肿瘤的两种成分及转移成分进行了第二代基因测序。
Herein, we report a unique case of metastatic basal cell carcinosarcoma, in which we analyzed the 2 components of the primary tumor as well as the metastasis by next-generation sequencing.
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