这表明二氯醋酸钠易于透过血脑屏障,改善脑内乳酸代谢。
It strongly suggests that DCA could readily penetrate the Blood-Brain-Barrier, and help improve the metabolism of brain lactic acid.
目的:建立药物透过血脑屏障的三维构效模型,为药物分子设计提供理论依据。
AIM: To construct 3d QSAR models of drugs passing through the blood brain barrier (BBB), that provide a theoretical basis for molecular drug design.
目的制备盐酸他克林(THA)的酰化前体药物以提高其透过血脑屏障(BBB)的能力。
Aim to synthesize acylated prodrug of tacrine hydrochloride (THA) to improve the infiltration ability across the blood brain barrier (BBB).
现在loannou实验室正在研究这种现象能够透过血脑屏障使脑细胞中的溶酶体释放溶菌酶去清除生理废物。
Now the Ioannou lab is studying whether this signal can also be transmitted across the blood-brain barrier to the lysosomes in brain cells to tell them to empty their stored waste products.
此外,根据线性溶剂化方程建立了定量结构-活性关系用于预测药物肠吸收、血脑屏障通透性和皮肤透过性。
Quantitative structure-activity relationships also have been established to predict drug intestinal absorption, permeation of skin and blood-brain barrier.
此外,根据线性溶剂化方程建立了定量结构-活性关系用于预测药物肠吸收、血脑屏障通透性和皮肤透过性。
Quantitative structure-activity relationships also have been established to predict drug intestinal absorption, permeation of skin and blood-brain barrier.
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