目的研究脊髓后正中点状切开术治疗顽固性癌性内脏痛的临床应用。
Objective: To study the effectiveness of punctate midline myelotomy (PMM)for the treatment of intractable visceral cancer pain.
背景:脑干孤束核是内脏痛信息向高位脑中枢传递的一个关键的中继站。
BACKGROUND:The nucleus tractus solitarius(NTS) is one of the key relay stations of various visceral primary afferent information.
目的探讨雌激素在延髓头端腹内侧部(rvm)对内脏痛的潜在调节作用。
Objective To examine the potential roles of estrogen in rostral ventromedial medulla (RVM) on visceral nociception.
方法:SD大鼠随机分成正常对照组,慢性内脏痛模型组和模型加电针组,每组6只。
Methods: SD rats were divided into control group, chronic visceral pain group and model with ea group, 6 rats in each group.
结果:电针能够显著降低内脏痛大鼠结直肠扩张刺激诱导的腹外斜肌放电幅值(P<0.05);
Results:The EA significantly decreased the electromyogram of abdominal external oblique muscle on colorectal expansionary irritation in chronic visceral pain rats(P<0.05).
结论:电针降低慢性内脏痛敏反应的镇痛机制与减少脊髓背角内CGRP样免疫阳性物质的表达有关。
Conclusion: the expressional decrease of CGRP-IR in spinal dorsal horn may be involved in the ea treatment in chronic visceral pain rat.
电刺激对侧的HCN也能抑制PO核中多数内脏痛反应神经元的活动,其抑制作用与同侧比较无明显差异。
The inhibition of HCN stimulation was bilateral and no statistical differences were found between the effects of contralateral and ipsilateral HCN stimulation on the neurons in PO.
虽然纤维肌痛是一种慢性疾病,但它不会损伤关节、肌肉或内脏器官。
While fibromyalgia is a chronic condition, it does not damage the joints, muscles, or internal organs.
实验组内脏牵拉痛发生率和术中呱替咙消耗总量明显低于对照组(P<0.05)。
The incidence of visceral pain and the consumption of intraoperative pethidine were significantly lower in experiment group than in control group (P< 0.05).
实验组内脏牵拉痛发生率和术中呱替咙消耗总量明显低于对照组(P<0.05)。
The incidence of visceral pain and the consumption of intraoperative pethidine were significantly lower in experiment group than in control group (P< 0.05).
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