雷帕霉素是一种大环内酯类抗生素。
本品为大环内酯类抗生素。
大环内酯类抗菌素和肾上腺皮质激素疗效效果。
Therapeutic effects of macrolides antibiotic and adrenal cortex hormone are effective.
目的建立大环内酯类抗生素微生物限度检查方法。
Objective To establish a method for microbial limit test of macrolide antibiotics.
目的了解大环内酯抗生素抗炎效应的细胞学机制。
Aim to evaluate the cellular mechanism of the anti inflammatory action of macrolide.
大环内酯类抗生素的基因工程研究进展十分迅速。
The study of gene engineering of macrolide antibiotics have made the rapid and exciting progress.
大环内酯类抗生素是治疗MP感染的有效抗生素。
Macrolides are the effective antibiotics in the treatment of MP infection.
本发明提供了一种大环内酯类化合物及其制备方法。
The invention provides a large ring lactone compound and a preparation method thereof.
氟代喹诺酮和大环内酯抗菌剂都与QT间期的延长有关。
Fluoroquinolones and macrolide antimicrobial agents have both been associated with prolongation of the QT interval.
目的：探讨大环内酯类抗生素的不良反应及用药安全性。
Objective: To study the macrolide antibiotic adverse reaction and safety of drug application.
目的研究酿脓链球菌对大环内酯类抗菌药物的耐药表型与基因型。
ABSTRACT Objective to investigate the macrolides resistant phenotype and genotype in Streptococcus pyogenes.
红霉素是一类广谱大环内酯类抗生素，在临床上具有广泛的应用。
Erythromycin is a broad spectrum macrolide antibiotic and clinically used widely.
目的研究酿脓链球菌对大环内酯类抗菌药物的耐药表型与基因型。
Objective to investigate the macrolides resistant phenotype and genotype in Streptococcus pyogenes.
目的：建立大环内酯类药物吉他霉素的高效毛细管电泳分离方法。
Objective: To establish a high performance capillary electrophoresis (HPCE) method for the separation of active ingredients in kitasamycin.
因此，开发新的抗耐药菌大环内酯抗生素已成为当前药物研究的热点。
Therefore, it has attracted extensive attention to develop new potent macrolides against resistant bacteria.
研究证实，多种大环内酯类抗菌素能影响中性粒细胞的功能，并诱导其凋亡。
It has been reported that many macrolides antibiotics may affect functions of neutrophil and induce its apoptosis.
结果表明，在维港海水中，只检出较低含量的氟喹诺酮和大环内酯类抗生素；
The results showed that the concentrations of antibiotics were mainly below the limit of quantification(LOQ) in the ambient marine water of Victoria Harbour.
罗红霉素为新型大环内酯类抗生素，其体外抗菌活性类似于母体化合物红霉素。
Roxithromycin, a new macrolide antibiotic, has an antibacterial spectrum similar to that of erythromycin.
四环素类、大环内酯类、喹诺酮类抗生素是治疗解脲支原体感染的主要有效药物。
Tetracyclines macrolides and quinolones are the effective antibiotics in the treatment of these diseases.
泰拉霉素是动物专用的新型大环内酯类抗生素，国内已批准用于猪呼吸系统疾病的防治。
Tulathromycin is a novel macrolide antibiotic for animals which has been approved for use in the prevention and treatment of swine respiratory disease in China.
结论：新一代大环内酯类抗生素阿奇霉素注射剂，治疗急性细菌性下呼吸道感染安全有效。
Conclusion: New generation of macrolides, azithromycin is a safe and effective antibacterial agent for the treatment of acute bacterial infections of lower respiratory tract.
因此，基于新靶点设计合成抗耐药菌大环内酯抗生素，是解决细菌耐药性的一条重要途径。
Therefore, design and synthesis of new macrolide derivatives against resistant bacteria based on new target sites is an important way to overcome bacterial resistance.
大环内酯类抗生素耐药菌比例比其他族类抗生素高，在医院环境中表现出最高的耐药菌比例；
Proportion of macrolide antibiotic was higher than other antibiotics and demonstrated the highest proportion in hospitals.
方法：查阅相关文献，按大环内酯类、喹诺酮类、四环素类分类对8种代表药物进行综合分析。
METHODS: By collecting the literatures and making aggregate analysis of 8 representative drugs depending on the classifications of macrolides, quinolones and tetracyclines.
最受人重视的抗生素是庆大霉素、最主要的特征是产生氨基糖苷类抗生素和大环内酯类抗生素。
It was found that production of aminoglycoside and macrolide antibiotics by the microorganisms was most characteristic.
本发明描述了大环内酯多烯抗生素或其衍生物或类似物作为培养物补充物用于病毒繁殖的用途。
The use of macrolide polyene antibiotics or derivatives or analogues thereof as culture supplement for the propagation of virus is described.
第二代大环内酯类抗生素具有良好的抗菌活性和酸稳定性，但是目前耐药性问题成为当务之急。
The second generation macrolide antibiotics has the satisfactory antibacterial activity and the stability in acid. But the tolerance has been the urgent problem.
红霉素是糖多孢红霉菌合成的次生代谢产物，为一类广谱大环内酯类抗生素，在临床上具有广泛的应用。
Erythromycin is the secondary metabolite of Saccharopolyspora erythraea. It is a broad spectrum macrolide antibiotic and clinically used widely.
抗菌机制研究表明：大环内酯抗生素的作用靶点位于50S亚基肽通道的出口处，紧邻肽酰转移酶中心。
The mechanism of macrolide's action indicates that the binding sites of macrolides are located inside the nascent peptide exit tunnel of the ribosomal 50S subunit near the peptidyl transferase center.
喹诺酮类、 大环内酯类、抗感染中成药类抗感染药物以及生物制品与生化药物、维生素类药物均有增长；
Anti-infectious agents like quinolones, macrolides, TCM with anti-infectious effect and biologicals & biochemicals, vitamins had grown.
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