目的：观察端粒酶反义寡聚脱氧核苷酸对人胃癌细胞株的作用。

To observe the effect of telomerase antisense oligodexynucleotides on gastric cancer cell line.

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结果：端粒酶反义寡聚脱氧核苷酸能诱导人胃癌细胞凋亡，抑制端粒酶活性。

Telomerase activity were detected by TRAPELISA. Results: Telomerase antisense oligodeoxynucleotides acted as a specific growth inhibitor to gastric cancer cell line.

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所以导入MDR1基因硫代反义寡聚脱氧核苷酸可以部分抑制SKOV3/mdr1细胞中MDR1基因的表达。

So MDR1 expression in SKOV3/mdr1 cell line was partially inhibited after MDR1-AS treatment in the mRNA and protein level.

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所以导入MDR1基因硫代反义寡聚脱氧核苷酸可以部分抑制SKOV3/mdr1细胞中MDR1基因的表达。

So MDR1 expression in SKOV3/mdr1 cell line was partially inhibited after MDR1-AS treatment in the mRNA and protein level.

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