相反，对于治疗指数相对狭窄的药物来说，生物利用度的差异就很重要。
In contrast, bioavailability differences are important for a drug with a relatively narrow therapeutic index.
通过观察细胞病变效应，用噻唑蓝(MTT)比色法检测细胞存活率，以确定该药物治疗指数。
By means of observing cytopathic effect and adopting MTT colorimetric assay for cell survival rate, their therapeutic index was calculated.
采用四甲基噻唑兰(MTT)比色法测细胞毒性作用，并计算细胞的存活率利治疗指数(TI)。
MTT method was used to evaluate the cytotoxicity, and the cell viability and therapeutic index (ti) was calculated.
许多抗肿瘤药具有治疗指数低的特征，其药代动力学在病人个体间存在较大的差异，而且具有较高毒性。
Most anticancer drugs are characterized by a narrow therapeutic index, wide inter patient variability of pharmacokinetic parameters and high toxicity.
1在流行国家采购的抗疟治疗药品方面存在指数增长：从2004年采购的400万以青蒿素为基础的联合治疗药物增至2005年3000多万。
There has been an exponential increase in anti-malarial treatments procured by endemic countries: from 4 million ACTs procured in 2004 to more than 30 million in 2005.
目的应用含美观量表的正畸治疗需求指数评价西安市正畸最适龄儿童在牙齿健康及牙齿美观基础上的治疗需求。
Objective To assess the need of orthodontic treatment in the adolescents of Xi′an city by using the index of orthodontic treatment need (IOTN).
目的：探讨低血糖指数膳食干预对2型糖尿病病人营养治疗效果的影响。
Objective: To observed the effect of nutrition therapy of low glycemic index foods on type 2 diabetic patients.
方法：采用DLQI研究银屑病患者治疗前、后的生活质量及其影响因素，并与传统的银屑病皮损面积和严重度指数(PASI)进行比较。
Methods: Compared with psoriasis area and severity index (PASI), DLQI was used to evaluate the life quality in the patients with psoriasis before and after treatment and its affecting factors.
通过对载波信号的频谱分析，提出了一种能分离治疗阈值与疼痛阈值的无极性指数脉冲。
After analyzing the spectrum of a group of signals, non-polar differential exponent pulse signal was selected as carrier wave, which can separate therapy threshold and ache threshold.
目的探讨正畸治疗中牙龈指数及龈沟液细菌的变化。
Objective To explore the changes of gingivitis index and bacteria in crevicular fluid during orthodontic treatment.
目的：评价高压氧、认知行为治疗和舍曲林对慢性失眠患者焦虑指数的影响。
OBJECTIVE To evaluate the effect of cognitive behavior treatment or high pressure oxygen therapy combined with sertraline on anxiety index in chronic insomnia patients.
观察治疗前后两组患者胰岛素抵抗指数（HOMA-IR）及凝血指标的变化。
The change of insulin resistance index(HOMA-IR)and the parameters of blood coagulation before and after treatment were observed.
观察治疗前后空腹血糖、餐后2小时血糖、空腹胰岛素、餐后2小时胰岛素及胰岛素敏感性指数的变化。
Before and after treatment, fast blood sugar and 2 hour post-meal blood sugar, fast insulin and 2 hour post-meal insulin and insulin sensitive index were measured.
治疗后eeg异常率下降到15.2%，血流速度及搏动指数降低，血管杂音消失。
EEG abnormality rate was 15.2%, flow velocity and pulsatility index were reduced and the vascular murmur disappeared after treatment.
比较治疗前后血压、左心室重量指数(LVWI)、空腹血糖、空腹胰岛素的变化。
The changes of blood pressure, left ventricular weight index (LVWI), fasting blood glucose (FBG) and fasting insulin before and after treatment were compared.
目的通过调查固定矫治器治疗中牙冠表面托槽周围的牙菌斑指数评价固定矫治器对龋病的影响。
Objective to evaluate the effect to caries of the fixed appliance by the investigation of plaque index on the crown surface of teeth at the different stages.
结果：本组患者治疗前后最长呼吸暂停时间、呼吸暂停低通气指数（AHI）、睡眠时最低血氧饱和度比较均有显著性差异（P<0.01）。
Results: The significant difference was found in the comparison of the longest time of apnea, AHI and the lowest oxygen saturation of blood in sleep before and after treatment (P<0.01).
观察治疗前后sle活动指数(SLEDAI)及各项免疫指标，血尿常规、肝肾功能及其他不良反应发生情况。
SLE disease activity index (SLEDAI), various immunological indexes, blood and urine routine, hepatic and renal function, as well as the other adverse reaction of the treatment were observed.
方法：应用彩色多普勒超声仪，检测ESWL治疗60例单侧肾结石病人过程中结石旁小血管阻力指数。
Methods: the intrarenal vascular resistance index in 60 patients was measured with Doppler ultrasound techniques before and after ESWL in the treated and contralateral kidneys.
目的验证恶性风险指数预测附件肿块良、恶性的准确性，探讨腹腔镜在可疑附件肿块治疗应用中的价值。
Objective to testify accuracy of the risk of malignancy index (RMI) to predict property of adnexal masses and to investigate application value of laparoscopy in treatment of suspected adnexal masses.
观察两组汉密尔顿(HAMD)量表及匹兹堡睡眠质量指数(PSQI)量表治疗前后的变化情况。
Changes of scores for Hamilton Depression Rating Scale (HAMD) and Pittsburgh Sleep Quality Index (PSQI) were investigated in the two groups.
治疗前后测定所有患者的血常规、体质量指数(BMI)和血清瘦素水平等。
Body mass index (BMI), blood hemoglobin (HGB) and serum leptin were examined pre-therapy and post-therapy in all patients.
全部病例在治疗前后均详细记录疼痛、压痛指数及肩部功能活动范围。
Pain index, tenderness index and activity ranges of the shoulder before and after treatment were evaluated.
目的：探讨影响乳腺癌脑转移放射治疗预后的因素并建立预后指数模型。
Purpose:To identify the prognostic predictors a nd to establish a prognostic index model for breast cancer patients with brain metastasis(BM) after irradiation.
目的评价甲真菌病临床评分指数(SCIO)指导伊曲康唑冲击和特比萘芬连续疗法治疗甲真菌病的疗效、安全性及费用疗效比。
Objective To assess the efficacy, safety and cost-effectiveness of itraconazole and terbinafine for the treatment of onychomycosis, evaluated by the scoring clinical index of onychomycosis (SCIO).
治疗后全血粘度、血浆比粘度、红细胞聚集指数及红细胞变形能力均有明显改善（均P<0.01）；
There was also a significant improvement on whole blood viscosity, blood plasma ratio viscosity, red blood cell aggregation index as well as red blood cell deformation (average P<0.01).
比较各组治疗前后羊水指数(afi)和相关凝血指标变化。
Amniotic fluid index (AFI) and coagulogram markers were compared before and after treatment in three groups.
结果实验组的菌斑指数和牙龈指数均有明显下降，治疗牙龈炎有效率较安慰剂组高。
Results The plaque index and gingival index of experiment group had decreased obviously, which effective rate in treatment of gingivitis was higher than that of placebo group.
肥胖指标方面，两组体重、体重指数、腰围、臀围治疗后较治疗前均有下降，两组比较下降程度无差别，腰臀比无明显变化。
Those obesity index such as body weight, body mass index(BMI), waist and hip line decreased significantly after the courses of treatment, and the degree of two groups is same.
指数回归分析结果显示，治疗组侧支血流越低，收缩功能恢复程度越明显。
The exponential regression analysis showed that the lower the collateral flow, the greater the recovery of function in treated dogs.
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