目的探讨人白细胞弹性蛋白酶(HLE)与其底物反应的最适条件,建立一种高通量的HLE抑制剂体外筛选模型。
ObjectiveTo explore the most suitable reaction condition for human leukocyte elastase (HLE) and its substrates, so as to establish a high-throughput in vitro screening model for HLE inhibitor.
结果C5暴露于组织蛋白酶G和弹性酶时,产生C5片段,而C5片段能使活化的白细胞释放MPO和乳铁传递蛋白。
Results C5 exposed to cathepsin G and elastase generated C5 fragments. C5 fragments stimulated primed neutrophil to release myeloperoxidase(MPO) and lactoferrin.
结果C5暴露于组织蛋白酶G和弹性酶时,产生C5片段,而C5片段能使活化的白细胞释放MPO和乳铁传递蛋白。
Results C5 exposed to cathepsin G and elastase generated C5 fragments. C5 fragments stimulated primed neutrophil to release myeloperoxidase(MPO) and lactoferrin.
应用推荐