本文综述了右旋美托咪啶的药理学、药物代谢动力学及其在重症监护病室中的临床应用，包括对谵妄的防治、药物本身的安全性和其特殊的可唤醒镇静效应。
This article reviewed the pharmacology, pharmacokinetics and its application in ICU, including its application in prevention and control of delirium, drug safety and its arousal sedation effects.
结论：中药药效决定于药物动力学参数及效应系数。
Conclusion: The effects of Chinese materia medica were all controlled by pharmacokinetic and pharmacodynamic coefficient.
体外释放第一天呈突释效应，而后药物释放基本符合零级动力学过程。
The pattern of drug release for 30 days in vitro fitted to zero order release plot, with an initial burst effect at the first day.
体外释放第一天呈突释效应，而后药物释放基本符合零级动力学过程。
The pattern of drug release for 30 days in vitro fitted to zero order release plot, with an initial burst effect at the first day.
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