根据鲑鱼降钙素基因的序列,合成了鲑降钙素基因。
Calcitonin gene was synthesized according to the sequence of salmon Calcitonin gene.
目的研究国产与进口鲑鱼降钙素喷鼻剂的生物等效性。
Objective to study the bioequivalence of imported and domestic of salmon calcitonin nasal spray in Chinese healthy volunteers.
目的评价鲑鱼降钙素喷鼻剂治疗原发性骨质疏松症的疗效。
To evaluate the curative effect of nasal spray of salmon calcitonin on primary osteoporosis.
鲑鱼降钙素含量显著下降,但是仍在质量标准规定的范围内。
The contents of salmon calcitonin were decreased during the storage period.
结论:新型嵌合降钙素活性高于人降钙素,而副作用较鲑鱼降钙素降低。
Conclusion: the activity of new calcitonin analogue was predicted to have higher bioactivity than that of human calcitonin, while the side-effects was lower than that of salmon calcitonin.
至术后第7天,鲑鱼降钙素的止痛效果则优于双氯芬酸钠双释放肠溶胶囊(P<0·05)。
On the 7th day after the operation calcitonin salmon was superior to Diclofenac sodium double release Intestine-sol Capsule(P<0.05).
目的探讨青壮年骨折患者长期卧床与骨量丢失、骨强度减低的关系及鲑鱼降钙素的预防作用。
Objective To probe the relationship between longterm bed and loss of bone mass and bone strength and the prevention of calcitionin in young patients with fractures.
结果:鲑鱼降钙素的不良反应临床表现主要为潮红、发热,其次为胃肠道反应,皮疹、神经系统反应和循环系统反应较少见。
RESULTS: The ADRs of calcitonin salmon were mainly manifested as flush and fever, next gastrointestinal disorders, while rash, disorders in nervous system and cardiovascular system were infrequent.
结果:鲑鱼降钙素的不良反应临床表现主要为潮红、发热,其次为胃肠道反应,皮疹、神经系统反应和循环系统反应较少见。
RESULTS: The ADRs of calcitonin salmon were mainly manifested as flush and fever, next gastrointestinal disorders, while rash, disorders in nervous system and cardiovascular system were infrequent.
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