... across the board统一，全面 against the grain（与某人的性格、情感或愿望等）格格不入；违反意愿 agree to disagree接受彼此不同的意见 ...
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... a big letdown 令人大失所望的事 against the grain 违反常规；违反本性 a dime a dozen 多得很；不稀罕、不值钱 ...
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go against the grain 令人讨厌或不高兴 ; 不合 ; 做违反情理或本性的事
Don't Go Against the Grain 唱片名
Cross-Dressers Against the Grain 变男变女变变变
reading against the grain 逆向阅读
go against the grain to 违反意愿做某事
以上来源于: WordNet
It really goes against the grain to have to work on a Sunday.
星期天还得上班的确不合常情。
Privatization goes against the grain of their principle of opposition to private ownership of industry.
私有化与他们反对产业私有制的原则相违背。
But what is asked of us here goes against the grain of our human nature.
但是，上主要求我们所做之事有违人性的本质。
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