These activities of the anti-CD44 antibody may be associated with its inhibitory effect on oncogene and anti-apoptosis protein expressions, and changes in mitochondrial membrane potential.
其作用机制可能与调节相关癌基因及抗凋亡蛋白的表达，降低线粒体膜电位有关。
Programmed cell death factor 4 (PDCD4) gene is a new anti-oncogene, which is firstly identified as a specific protein expressed in cell apoptosis.
程序性细胞死亡因子4 (PDCD4)基因是首先在细胞凋亡中因一种表达特异的蛋白质而鉴别出来的一种新的抑癌基因。
JANEX-1 exhibits significant anti-leukemia activity, which could induce apoptosis in human lymphoblastic as well as myeloblastic leukemia cells with over-expressed tyrosine protein kinase.
JANEX - 1具有良好的抗白血病活性，它可诱导酪氨酸蛋白激酶过度表达的淋巴性白血病细胞和髓性白血病细胞凋亡。
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