OBJECTIVE a method was developed for the determination of Dxamethasone Acetate in calcium alginate gel beads and observed the release properties of gel beads in different media.

目的建立一种方法测定海藻酸钙凝胶小球中醋酸地塞米松的含量，考察小球在不同介质中的溶出性能。

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Two different methods, addition and displacement were adopted so as to improve the strength of calcium-alginate beads, and the best immobilized condition was adopted.

针对海藻酸钠载体强度低、易分解的缺点，采用添加法和置换法对载体进行改性研究，并确定了最佳固定化条件。

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Calcium alginate gel beads were widely used as drug carriers, which were obtained by the gelation of sodium alginate with divalent cation as Ca2 +.

目前，海藻酸钠与二价钙离子交联反应形成的海藻酸钙凝胶小球作为药物的载体日益受到广泛的应用。

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