gene disruption 基因破坏 ; 基因中断 ; 基因敲除 ; 断技术
gene-disruption 基因敲除
gene disruption technique 基因中断技术
gene double disruption 基因双敲除
gene disruption and replacement 基因破坏和基因替换
It is marked by a mutation in a gene known as RPE65 which results in a missing enzyme that leads to degradation of the retina and the disruption of vision processing in the brain.
这种病的特点是，一段名为RPE65的基因发生变异，导致缺失，进而引起视网膜退化，大脑视觉处理中断。
Intronic mutations may affect gene regulation through aberrant splicing or disruption of critical DNA protein interactions.
内含子突变可以通过引起剪接异常或关键性DNA -蛋白反应中断而影响基因调控。
Most importantly, such a precise gene disruption in the nervous system will allow us to study specific roles of candidate genes in neurodegenerative diseases that afflict the aging.
更为重要的可能在于，在神经系统中有目的干扰某个基因的表达，对影响寿命的有关神经退行性疾病的研究将会有所助益。
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