方法以硬脂酸为载体采用溶剂乳化法制备水飞蓟素固体脂质纳米粒,并用葡聚糖凝胶层析法测定其包封率。
Method Silymarin SLN was prepared through the solvent-emulsifying method with stearic acid as the carrier, and the encapsulation rate was determined with the Sephdex gel chromatogram.
以自制芹菜素混悬液为对照组,考察了大鼠口服芹菜素固体脂质纳米粒的药动学过程。
The pharmacokinetic processes of oral AP-SLN of the rats were also studied, while apigenin suspension was used as control group.
结果超滤法能有效地将石杉碱甲固体脂质纳米粒与游离石杉碱甲分离,回收率为98.09%,测得3批样品的平均包封率为57.63%。
Results Free drugs could be effectively separated from the Hup ASLN by ultrafiltration. The average entrapment efficiency of three batches of Hup ASLN was 57.63%, with the recovery of 98.09%.
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