随着聚乙二醇基链长的增加，药物对乙酰胆碱酯酶抑制活性依次减弱。
With an increasing chain length of polyethylene glycol group linked on niclosamide, the inhibitory effects weakened.
摘要：采用微量筛选模型考察48种中药提取物的乙酰胆碱酯酶抑制活性。
Abstract: in this paper, the acetylcholinesterase (AChE) inhibitory activities of 48 traditional Chinese medicine extracts were investigated by microscale screening model.
本文利用簇合效应原理，合成了一些对乙酰胆碱酯酶抑制活性较好的化合物，为今后的研究工作提供了很好的基础，值得进一步深入开展这方面的研究。
In summary, we designed and synthesised some bivalent compounds as potential AChE inhibitors by cluster effect, the study provides a basis for the further related work and were worth further studying.
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