目的：制备米托蒽醌固体脂质纳米粒并优化其处方组成。
OBJECTIVE to prepare and optimize the composition of mitoxantrone solid lipid nanoparticles.
方法用水性溶剂扩散法，制备得到甘油单硬脂酸酯固体脂质纳米粒。
Methods Monostearin solid lipid nanoparticles was prepared by solvent diffusion method in aqueous system.
方法以硬脂酸为载体采用溶剂乳化法制备水飞蓟素固体脂质纳米粒，并用葡聚糖凝胶层析法测定其包封率。
Method Silymarin SLN was prepared through the solvent-emulsifying method with stearic acid as the carrier, and the encapsulation rate was determined with the Sephdex gel chromatogram.
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