...论文 Array-CGH检测37例PTCL-NOS染色体改变,并使用Tile path array-CGH和荧光原位杂交技术(fluorescence in situ hybridization,FISH)验证其部分结果。根据克隆性分析结果、形态学特征和提取DNA质量,最终确定本研究对象。
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通过靶向测序和荧光原位杂交技术发现，3例均存在ZC 3h7b - BCOR基因融合。
All 3 ESS were found to harbor ZC3H7B-BCOR gene fusions by targeted sequencing and fluorescence in situ hybridization.
目的探讨用多色荧光原位杂交(M FISH)技术检测的易位和双着丝粒染色体畸变的差异。
Objective To explore the differences between radiation-induced translocation and dicentric chromosome aberrations detected by multicolor fluorescence in situ hybridization (M-FISH) method.
通过粗线期染色体荧光原位杂交技术，将发生易位的第6号和第12号染色体的易位点分别锚定在1个和3个BAC克隆库中。
Transpositional points between chromosome 6 and 12 were anchored in 1 and 3 BAC clone's pool respectively by fluorescence in situ hybridization technology of pachytene chromosomes.
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