自体干细胞移植在滤泡性淋巴瘤的一线治疗中除临床试验之外不宜采用。(证据等级:强,中等)。
Autologous stem cell transplantation has no role in first line therapy for FL outside a clinical trial (Strong, Moderate).
在一个30例患者的小规模研究中,pidilizumab加利妥昔单抗在复发的滤泡性淋巴瘤中取得了66%的总有效率,其中大部分是完全缓解。
In a small 30-patient study, pidilizumabplus rituximab demonstrated an ORR of 66% in relapsed follicular lymphoma, which primarily consisted of complete responses.
阐释:滤泡性淋巴瘤患者在免疫化疗作为一线治疗后使用利妥昔单抗维持治疗2年,能显著改善无进展生存(PFS)。
INTERPRETATION: 2 years of rituximab maintenance therapy after immunochemotherapy as first-line treatment for follicular lymphoma significantly improves PFS.
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