和ER8 基因敲除鼠(BERKO),以及 ERaER~双 基因敲除鼠(DERKO).免疫学家借助这些基因敲除鼠对 ERct 和 ERB 在免疫系统中的重要组织进行了一系列相关 的研究,...
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雌性野生种小鼠的丙氨酸转氨酶是基因敲除鼠的4倍,这提示肝损伤的存在;
Female wild-type mice on an ethanol-rich diet had 4 times as much alanine aminotransferase (ALT), indicating liver injury, than mice lacking the osteopontin gene.
研究者们从遗传上敲除了结肠癌鼠模型和人类结肠癌细胞系的ERBB3基因。
The researchers genetically blocked ERBB3 in a mouse model of colon cancer and in human colon cancer cell lines.
他们发现这种敲除基因的小鼠骨髓中的淋巴细胞较正常鼠少50%,产生特异免疫细胞的胸腺较正常鼠少80%。
They found that the knockout mice had 50 percent fewer lymphocytes in their bone marrow and 80 percent fewer in their thymus, a collection of glands that helps produce specialized immune cells.
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