目的研究抗血管内皮生长因子(VEGF)对胃癌生长和转移的抑制作用。
Objective to study the inhibiting effect of anti vascular endothelial growth factor (VEGF) on the growth and metastasis of gastric cancer.
对手术标本进行抗CD34因子及抗VEGF因子免疫组化染色,测量肿块微血管密度计数及血管内皮生长因子(VEGF)阳性表达率,与超声彩色像素密度值相比较。
The microvessel density and vascular endothelial growth factor was measured in surgical specimen after immunohistochemical staining using anti-factor CD34, VEGF and compared to color pixel density.
结论:异种血管内皮生长因子基因重组T7噬菌体疫苗可打破机体对自身vegf的免疫耐受,诱导产生较高水平的特异性抗vegf抗体。
Conclusion: Recombinant T7 phage vaccine expressing xenogenic VEGF can break immunologic tolerance against self-VEGF and induce the producing of specific anti-VEGF antibody.
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