Survivin是细胞凋亡抑制蛋白(inhibitorofapoptosisfamilyof proteins,IAPs)家族中新近发现的成员,其组织分布具有明显的细胞选择性, 研究表明它表达于胚胎和发育的胎儿组织,而未见...
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凋亡抑制蛋白在抑制细胞凋亡中起非常重要的作用,XIAP是IAP家族中抑制细胞凋亡的最主要成员。
The inhibitor of apoptosis protein plays important role in suppressing apoptosis of cells. XIAP is the most important member of IAP family.
结论5f能抑制体外微管蛋白聚合,从而可能是影响细胞的细胞周期及诱导凋亡途径之一。
Conclusion 5f inhibits tubulin polymerization and depolymerization, and leads to cell cycle arrested, and possibly induces apoptosis.
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