高浓度碘对甲状腺滤泡细胞(thyroid follicular cell,TFC)具有直接毒性作用,这可能导致甲状腺自身抗原的释放而引起甲状腺自身免疫反应(1)。1.
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TTF蛳1在甲状腺常见良恶性病变中阳性率均高,特异地表达在细胞核,是一种特异的甲状腺滤泡细胞标志物。
TTF, 1 was expressed in the majority of benign and malignant thyroid diseases. The immnostaining of TTF, 1 was located in nuclear of cells, TTF, 1 was a sensitive marker for thyroid follicular cells.
应用免疫过氧化酶技术鉴定甲状腺球蛋白和甲状腺素在甲状腺组织中的分布,可以了解甲状腺滤泡细胞的功能状态。
Employing immunoperoxidase technique to determine the distribution of thyroglobulin and thyroxine in the thyroid made us possible to understand the functional state of follicular cell.
钠碘转运体(NIS)介导甲状腺滤泡细胞的碘浓聚,从而成为多种甲状腺良恶性疾病诊断和治疗的分子生物学基础。
Sodium iodide symporter (NIS) mediates the accumulation of iodide in thyroid follicular cells, and becomes the molecular biology basis to diagnose and treat benign and malignant thyroid diseases.
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