中国生物制品学杂志 (Liver pyruvate kinase,LPK)基因mRNA的表达水平,Westernblot分析细胞脂肪酸合成酶(Fatty acid synthase,FAS)蛋白的表达水平。结果 与对照组比较,高糖可使L02细胞内甘油三酯和脂滴含量增加,刺激ChREB
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“也许有可能,例如说,将人类的巨噬细胞提取出来,抑制这些细胞中的脂肪酸合成酶,然后再将这些细胞注入同一个人的身体中,”他说。
"It may be possible, for example, to take macrophages out of humans, inhibit fatty acid synthase in those cells, and then infuse the macrophages back into the same person," he says.
这些老鼠实验暗示锁定巨噬细胞中的脂肪酸合成酶可能为人类提供潜在治疗策略。
These mouse experiments suggest targeting fatty acid synthase in macrophages may provide a potential treatment strategy for humans.
目的研究黄芩素对3 T3 - L 1小鼠前脂肪细胞分化及对脂肪酸合成酶活性的影响。
Objective to study the effects of baicalein on differentiation of 3t3-l1 murine preadipocytes into adipocytes and on the activities of fatty acid synthase (FAS).
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