目的探索低剂量醋酸棉酚(GA)组合甲基睾酮(MT)及炔雌醇(ee)抗雄性生育作用的可行性及优化方案。
Objective: to study the feasibility and optimal regimen of oral low dose gossypol acetate (GA) combined with methyltestosterone (MT) plus ethinyl estradiol (EE) for contraception in male rats.
醋酸棉酚作为一种男性避孕药，已进入实用阶段，在医药、化工、机械等很多领域有广阔的应用前景。
As a kind of male prophylactic, gossypol acetic acid has been applied comprehensive in many fields, such as medicine chemical engineering and technical engineering.
与原位缺口翻译实验相对应，集落形成试验表明，在高浓度醋酸棉酚或GTW作用下，细胞失去繁殖的能力；
In a colony-forming test, we found that the cells lost their proliferate ability, since no colonies could be formed, if gossypol or GTW were of high concentration;
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