应对气候变化是一项需要全球协力的重大课题。

Addressing climate issue is a global assignment that requires combined efforts.

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混凝土耐久性是国际工程界关注的重大课题。

Durability of concrete is an important subject respected by international engineering circle.

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那时大学里科学辩论的重大课题是生命的“自发生说”。

The great scientific debate in universities at that time was "spontaneous generation" of life.

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Cell proliferation is a huge issue in cell culture.

细胞增殖是细胞培养中的重大课题

耶鲁公开课 - 生物医学工程探索课程节选