脂质体是磷脂依靠疏水缔合作用在水中自发形成的一种分子有序组合体，为多层囊泡结构，每层均为类脂双分子膜，\n\n长循环脂质体层间和脂质体内核为水相，双分子膜间为油相，膜厚度约为95+。
长循环脂质体（long-circulating liposome）：经PEG修饰以增加柔顺性和亲水性，通过单核-巨噬细胞系统吞噬，减少脂膜与血浆蛋白的相互作用，延长循环时间。
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... liposome entrapment 脂质体包载 circulating liposome 长循环脂质体 LIPOSOME OXYGEN 微脂囊氧分子 ...
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修饰长循环脂质体 AF-linked st erically stabilized liposomes
顺铂长循环纳米脂质体 LDDP
长循环热敏脂质体 long circulating thermosensitive liposomes ; LTSL
长循环固体脂质纳米粒 long circulating solid lipin nanoparticles
The long-circulating liposomes were prepared with DTX and the effect of some factors on the encapsulation efficiency was investigated. Then the formulation was optimized by the response surface methodology.
以多西他赛为模型药物制备了多西他赛长循环脂质体,实验以包封率为指标考察了处方及工艺对制剂包封率的影响,并以效应面法确定优化处方。
参考来源 - 叶酸受体介导多西他赛肿瘤靶向长循环脂质体的研究The apparent partition coefficients of VIN in different pH value PBS were determined. Long-circulation liposome was prepared by the membrane extrusion method.
本文采用薄膜分散-挤压法制备长春西汀长循环脂质体,并采用超速离心法测定了脂质体的包封率。
参考来源 - 长春西汀长循环脂质体的研究·2,447,543篇论文数据，部分数据来源于NoteExpress
结论：长循环脂质体是长春新碱的理想载体。
Conclusions: Long-circulating liposome is a good drug delivery system for vincristine.
方法用乙醇注入合并硫酸铵梯度法制备米托蒽醌长循环脂质体。
METHODS the long circulating mitoxantrone liposomes were prepared by ethanol injection combined with the ammonium sulphate gradients method.
方法采用乙醇注入合并硫酸铵梯度法制备米托蒽醌长循环脂质体。
METHODS The long circulating mitoxantrone liposomes were prepared by ammonium sulphate gradients method.
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