颗粒酶是外源性的丝氨酸蛋白酶,来自细胞毒淋巴细胞(CTLs)和自然杀伤细胞(NK)释放的细胞浆颗粒。
ObjectiveTo investigate the levels of perforin and granzyme B expressions in T lymphocyte subsets in the protective immune against tuberculosis.
目的研究结核病初期T淋巴细胞亚群内穿孔素和颗粒酶B的表达水平。
参考来源 - 结核病初期T淋巴细胞亚群内穿孔素和颗粒酶B的检测·2,447,543篇论文数据,部分数据来源于NoteExpress
细胞毒性颗粒中含有包裹在蛋白多糖基质中的穿孔素和一类被称作颗粒酶的丝氨酸蛋白酶。
Cytotoxic granules contain perforin and a group of serine proteases called granzymes in a proteoglycan matrix.
颗粒酶b与自身免疫疾病及抗病毒感染密切相关,在恶性肿瘤细胞杀伤方面的应用价值正日益受到关注。
Granzyme B is closely related to autoimmune diseases and anti-virus infection process. It is attracting increasing attention for its application in cancer treatment.
钱博士又改良了染色颗粒使之对其他的分子也能产生作用,比如被称作凝血酶的血液凝固因子。
And Dr Tsien has even modified the dye to respond to other molecules, such as a blood-clotting factor called thrombin.
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