鉴于细辛的毒性及临床用量,古今众说纷纭,目前普遍认为细辛的毒性,主要是其挥发油成份中所含黄樟醚(Safrole)所致,但黄樟醚的中毒剂量(浓度)是多少?国内尚未见报道;临床常用剂量究竟应该用多少?
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公斤/桶中文名称：素 英文名称：Safrole又叫：又叫脑，油素，5-(2-丙烯基)-1，3-苯间二氧杂...... 查看全部详细描述>> 广东东莞中盛化工有限公司其他相关产品信息 供应广东广西胡椒
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Safrole contents of the extracts were 94.9%,36.1% and 15.9%,respectively,analyzed by GC,which was confirmed by GC-MS. For the substances of molecular weight between 30-550u,the essential oil produced by steam distillation contained α-limonene,linalool and 2-methyl-3-(2-propenyl)phenol besides safrole.
采用气相色谱-质谱联用法对气相色谱法进行了确证,测得水蒸气蒸馏法制备的精油中分子质量在30～550 u范围的物质,除黄樟油素外,还含有α-柠檬烯、芳樟醇、2-甲基-3-(2-丙烯基)苯酚。
参考来源 - 三种方法制备的岩桂叶精油(浸膏)的分析·2,447,543篇论文数据，部分数据来源于NoteExpress
N a colourless or yellowish oily water-insoluble liquid present in sassafras and camphor oils and used in soaps and perfumes. Formula: C10H10O2 黄樟油精
Synthetic methods of vanillin include o-methoxyphenol method, lignin method, safrole method, eugenol method, methyl hydroxybenzene method and microbial method.
生产方法主要有愈创木酚法、 木质素法、 黄樟素法、 丁香酚法、 甲酚法和微生物法等。
In GC-MS analysis, 9 major constituents accounting for 86.1% of the total essential oil, of which methyleugenol (22.9%) was the most, followed by safrole (19.8%).
结果表明：有9种含量大于1%的化学成分占北细辛挥发油总量的86.1%，其中甲基丁香酚含量最高（22.9%），其次为黄樟醚（19.8%）；
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