There are no records of a human having been intentionally kept awake long enough to kill them, but a hereditary disease called fatal familial insomnia suggests there is an ultimate limit.

没有关于一个人类被迫保持不睡的时间久到死亡的记录，但是有一种叫做致命性家族失眠症的遗传病似乎表明人类无睡眠时间是有极限的。

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However, he said, understanding the molecular nature of this single genetic defect, which is at the root of a familial form of such a complex disease, offers invaluable clues.

然而，他又说，理解单个遗传缺陷的分子本质，其是如此复杂疾病的一种家族性形式的根源，提供了无价的线索。

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Cross's disease, familial amyloidosis, prevents the liver from breaking down a protein called transthyretin.

克罗斯患有一种其家族特有的淀粉样变性疾病，它使肝脏无法分解一种叫做转体基因的蛋白。

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Celebrex has been approved for preventing the formation of potentially cancerous polyps in FAP, or familial adenomatus polyposis, a familial disease that causes them to form more frequently.

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It shows promise for all forms of high cholesterol, but the prospects are best in a rare disease called familial hypercholesterolemia (FH).

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The ENHANCE study was conducted in 720 patients with heterozygous familial hypercholesterolemia, a genetic disease that can boost untreated cholesterol levels above 300.

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