技术文摘 关键词:豆豉,萃取,乙酰胆碱酯酶抑制剂,大孔吸附树脂 [gap=1426]Key words：Douchi;extract;acetylcholinesterase inhibitor;macroporous resin
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inhibitor of acetylcholinesterase 乙酰胆碱酯酶抑制剂
ⅡConstruction of acetylcholinesterase inhibitor screening modelAcetylcholinesterase (AChE) hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission.
Ⅱ乙酰胆碱酯酶抑制剂筛选模型的构建乙酰胆碱酯酶(acetylcholinesterase，AChE)在神经肌肉接头和脑胆碱能突触水解神经递质乙酰胆碱，来终止神经递质对突触后膜的兴奋作用，保证神经信号的正常传递。
参考来源 - 孕烷X受体配体筛选模型与乙酰胆碱酯酶抑制剂筛选模型的构建·2,447,543篇论文数据，部分数据来源于NoteExpress
Usage: The second generation of central acetylcholinesterase inhibitor, used as a highly selective and reversible treatment of Alzheimer's disease.
用途：第二代中枢性乙酰胆碱酯酶抑制剂，是一只具有高度选择性、可逆性治疗阿尔茨海默病（老年痴呆）的药物。
OBJECTIVE To investigate the nasal absorption of huperzine A, which is a reversible acetylcholinesterase inhibitor for the treatment of Alzheimers disease.
目的研究治疗早老性痴呆症药物石杉碱甲的鼻黏膜吸收特性。
The systematic pharmacological study shows that this alkaloid possesses good anticholinesterase effect, and therefore it is a new structure type of reversible acetylcholinesterase inhibitor.
经过系统药理学研究表明，该生物碱具有良好抗胆碱酯酶效应，从而可认为该生物碱系一种新结构类型的可逆性胆碱酯酶抑制剂。
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