...知结构蛋白质作用最接近的蛋白质结构,例如配体结合的接受器 (ligand-bound receptor)、酵素的活性部位(active site of an enzyme)、蛋白质状态 close-form/open-form 及其他等等。
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For instance, they might construct a compound that inhibits the active site of an enzyme crucial to viral reproduction.
举例来说，他们可以设计某个化合物，作用在病毒复制时不可或缺的酵素活性区，而加以抑制。
The catalytic center of an enzyme is composed of a set of amino acids whose three-dimensional arrangement forms the "active-site" that allows them to efficiently bind and modify the substrate.
酶的催化中心是由一组氨基酸组成，其三维结构形成活性位点，允许它高效地结合或修饰底物。
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