We need to settle this once and for all.

我们需要把这事一次解决。

《牛津词典》

All that was needed was one final push, and the enemy would be vanquished once and for all.

只需要最后一次挺进，敌军就将被彻底击败。

《柯林斯英汉双解大词典》

I need to have it out with her once and for all.

我有必要跟她公开彻底地把话说清楚。

《牛津词典》

I will give you all development and all you have to do is every once in five years make sure you come and vote for me, and this thing will go on,"

VOA: standard.2010.02.24

You just need to remember what's happening to z effective, which really tells us what's happening with all the trends, and once you know z effective, you can figure out, for example, what direction the atomic radius should be going into.

你只需要记住有效核电量的规律，实际上它会告诉我们所有的规律，只要你知道了有效核电量的规律，你就可以判断，比如，原子半径会向着哪个方向发展。

麻省理工公开课 - 化学原理课程节选

First, the Treaty declared that the individual sovereign state would henceforth become the highest level of authority; you might say, putting an end once and for all " to the universalist claims of the Holy Roman Empire.

第一，条约宣称,各个主权国家,都因此而成为各自国家里最高的权力;,永远终结了,普遍意义上的“神圣罗马帝国。

耶鲁公开课 - 政治哲学导论课程节选

Maybe this continuing lack of care for the planet and its people will one day become the reason we leave Earth for once and for all.

BBC: Viewpoint: Should we send humans to Mars?

The public must put pressure on state and government to use all its resources to once and for all finish the Taliban.

FORBES: Attack On Pakistani Teen Turns Nation Against The Taliban

"You can go with John McCain's plans to do nothing, or you can stand side-by-side with me and Hillary Clinton and finally, once and for all, provide the health care that every American needs, " he said.

CNN: Obama: Campaign proved 'the progress we have made'